Product Manual

suture sizes, the knot breaking strength for Polysorb™ sutures was significantly
greater than that encountered by Polyglactin 910™ sutures. In addition, the mean
maximum knot rundown force encountered with the Polysorb™ sutures was
significantly lower than that noted with the Polyglactin 910™ sutures, facilitating
knot construction.
The surfaces of the Polysorb™ sutures have been coated to decrease their
coefficient of friction.
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The new Polysorb™ suture is coated with an absorbable
mixture of caprolactone/glycolide copolymer and calcium steraroyl lactylate. At
14 days post-implantation, nearly 80% of the USP (United States Pharmacopoeia)
tensile strength of these braided sutures remains. Approximately 30% of their
USP tensile strength is retained at 21 days. Absorption is essentially complete
between days 56 and 70.
We recently studied the determinants of suture extrusion following subcuticular
closure by synthetic braided absorbable sutures in dermal skin wounds.
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Miniature swine were used to develop a model for studying suture extrusion.
Standard, full-thickness skin incisions were made on each leg and the abdomen.
III. scientific basis for the selection of surgical sutures (cont’d)
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