User manual

1260 Nanoflow Pump User Manual 77
Optimizing Performance
5
How to Optimize the Compressibility Compensation Setting
5 Starting with a compressibility setting of 10 × 10
-6
/bar increase the value
in steps of 10. Re-zero the integrator as required. The compressibility
compensation setting that generates the smallest pressure ripple is the
optimum value for your solvent composition.
6 Repeat step 1 on page 76 through step 5 on page 77 for the B channel of
your pump.
Tabl e 19 Solvent Compressibility
Solvent (pure) Compressibility (10-6/bar)
Acetone 126
Acetonitrile 115
Benzene 95
Carbon tetrachloride 110
Chloroform 100
Cyclohexane 118
Ethanol 114
Ethyl acetate 104
Heptane 120
Hexane 150
Isobutanol 100
Isopropanol 100
Methanol 120
i-Propanol 100
To l u e n e 8 7
THF 95
Water 46