SDS

Product name: GREAT STUFF™ Big Gap Filler Insulating Foam
Sealant 12oz HC ES SASTW 12ct
Issue Date: 06/07/2018
Page 10 of 19
Contains component(s) which are classified as specific target organ toxicant, single exposure,
category 3.
Specific Target Organ Systemic Toxicity (Repeated Exposure)
Tissue injury in the upper respiratory tract and lungs has been observed in laboratory animals after
repeated excessive exposures to MDI/polymeric MDI aerosols.
Contains component(s) which have been reported to cause effects on the following organs in animals:
kidney
Liver.
Carcinogenicity
Lung tumors have been observed in laboratory animals exposed to respirable aerosol droplets of
MDI/Polymeric MDI (6 mg/m3) for their lifetime. Tumors occurred concurrently with respiratory
irritation and lung injury. Current exposure guidelines are expected to protect against these effects
reported for MDI.
Teratogenicity
In laboratory animals, MDI/polymeric MDI did not cause birth defects; other fetal effects occurred only
at high doses which were toxic to the mother. Contains component(s) which caused birth defects in
laboratory animals only at doses toxic to the mother.
Reproductive toxicity
Based on information for component(s): May cause harm to breastfed babies.
Mutagenicity
In vitro genetic toxicity studies were negative for component(s) tested. Genetic toxicity data on MDI
are inconclusive. MDI was weakly positive in some in vitro studies; other in vitro studies were negative.
Animal mutagenicity studies were predominantly negative.
Aspiration Hazard
Based on physical properties, not likely to be an aspiration hazard.
Carcinogenicity
Component
List
Classification
Paraffin waxes and
Hydrocarbon waxes,
chlorinated
IARC
Group 2B: Possibly carcinogenic to
humans
US NTP
Reasonably anticipated to be a human
carcinogen
12. ECOLOGICAL INFORMATION
Ecotoxicological information appears in this section when such data is available.
Toxicity
Polymethylenepolyphenylisocyanate, propoxylated glycerin polymer
Acute toxicity to fish
For this family of materials:
Material is practically non-toxic to aquatic organisms on an acute basis
(LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested).