SDS

NEONIX Co., Ltd.
Date: Feb 22, 2022
MODEL VCA-RBT95 / DJ96-00234A
ACGIH
- Nickel : A5
- Cobalt and cobalt compounds : A3
- Aluminum : A4
- Carbon black : A3
KOREA-ISHL
- Cobalt and inorganic compounds : 2
- Carbon black : 2
- Nickel : 1A
EU
- Lithium nickelate : Carc.1A
- Nickel : Carc.2
- Copper : EPA IRIS: D In carcinogenicity study with rat, tumor was not observed.
- Polyethylene : Fifty rats were implanted with polyethylene. In the polyethylene group, 23 developed
tumors (two of these were unrelated to the implants).
Mutagenicity :
- Graphite : Negative reactions were observed in vitro (Bacterial Reverse Mutation Assay(OECD
Guideline 471, GLP)).
- Fe : In mammalian cell gene mutation assay electrolytic iron, positive carbonyl iron exhibited a
cytotoxic and mutagenic response (OECD TG 476)
- Copper : Negative reactions were observed in both in vitro(Ames test) and in vivo(DNA damage
and/or repair; unscheduled DNA synthesis, micronucleus assay). (GLP)
- Dimethyl carbonate : Negative reactions were observed in both in vitro (Mammalian Chromosome
Aberration Test (OECD Guideline 473, GLP)) and in vivo (Mammalian Spermatogonial Chromosome
Aberration Test (OECD Guideline 483))
- Aluminum : Negative reactions were observed in vitro (mammalian cell gene mutation assay with
mouse lymphoma L5178Y cells(OECD TG 476, GLP)) and in vivo (micronucleus assay with rats
(OECD TG 474, GLP)). (Aluminium hydroxide, aluminium chloride, aluminum oxide; read across)
- Polyethylene : Negative reactions were observed in Ames test using Salmonella typhimurium and
Escherichia coli.
- 1,3-Dioxolan-2-one : Negative reactions were observed in vitro (mammalian cell gene mutation
assay (OECD Guideline 476, GLP)).
- Lithium hexafluorophosphate(1-) : Negative reactions were observed in both in vivo (Mammalian
Erythrocyte Micronucleus test(OECD Guideline 474)) and in vitro (Bacterial Reverse Mutation
Assay(OECD Guideline 471, GLP)).
- Ethyl acetate : Negative reactions were observed in both in vitro(Bacterial Reverse Mutation
Assay(OECD Guideline 471)) and in vivo (Mammalian Erythrocyte Micronucleus Test(OECD
Guideline 474)).
- Carbon black : Negative reactions were observed in both in vitro(Bacterial gene mutation test(OECD TG
471, GLP), Chromosomal aberrations test(OECD TG 476)) and in vivo(DNA damage and/or repair test).
- Lithium carbonate;Lithane : Negative reactions were observed in vitro (Bacterial Reverse Mutation
Assay(OECD Guideline 471, GLP)).
- 1-Methyl-2-pyrrolidinone : Negative reactions were observed in both in vitro (Chromosomal
aberrations test (OECD Guideline 476, GLP)) and in vivo (Mammalian Erythrocyte Micronucleus Test
(OECD Guideline 474, GLP)).
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