SDS

SAMSUNG SDI Co., Ltd.
Date: January 2
nd
2020 Revision no.: 01
MODEL INR18650-22P
Page 16 of 22
with water/moisture))
- Carbon black : No adverse effects on the reproductive function are expected.(OECD TG 414)
Specific target organ toxicity (single exposure) :
- Fe : If inhaled, iron is a local irritant to the lung and gastrointestinal tract.
- Copper : All animals showed expected gains in bodyweight over the study period and there were no
abnormalities noted at necropsy. (OECD TG 423, GLP)
- Aluminum : In test using rats, Clinical signs of depression, laboured respiration, piloerection and
hunched appearance was noted at the highest dose 15900 mg/kg. Macroscopic examination at the
end of the observation period did not reveal any aluminium-related changes of the internal organs of
the aluminium treated animals compared to the control group. (OECD TG 401)(Fumed alumina; read
across)
- Polyethylene : No test substance-related toxic effects were observed in an acute oral toxicity study
with rats.
- Lithium hexafluorophosphate(1-) : Clinical signs observed during the study period were lethargy,
hunched posture, uncoordinated movements, piloerection at 300 mg/kg, hunched posture, piloerection
at 50 mg/kg. The surviving animals had recovered from the symptoms by Day 3.(OECD Guideline 423,
GLP)
- Carbon black : No effect on endothelins or blood pressure was observed after exposure to carbon
black. There were also no effects on body temperature and activity of the animals.
- Nickel; Raney nickel : In the acute oral toxicity using rat, there were no effects on clinical signs,
systemic toxicity.(OECD Guideline 401, GLP)
Specific target organ toxicity (repeat exposure) :
- Fe : Rats were exposed to metallic iron as carbonyl iron via their feed (2.5%) for 2, 4, 6, or 9 weeks.
This resulted in a strong increase of non-heme iron in the liver and clear lipid peroxidation in the liver
and the mucosa of the duodenum. No evidence for DNA breakage were found. What follows is the
original abstract of the publication. (carbonyl iron)
- Copper : In test with rats for 92 days, there were no mortalities or signs of clinical toxicity observed in
any of the test species during the duration of the study. Opthalmoscopic examinations revealed no
abnormalities at any dose level tested. At gross pathology, significant decreases in heart and kidney
weight were noted in the high dose males in the thymus and kidneys of high dose females. (GLP)
- Aluminum : On occasion workers chronically exposed to aluminum-containing dusts or fumes have
developed severe pulmonary reactions including fibrosis, emphysema and pneumothorax.
- Polyethylene : No significant adverse effects were observed in subchronic (90-day) oral toxicity study
with rats and dogs.
- Lithium hexafluorophosphate(1-) : According to expert review of fluoride intake and effects on human
health, fluoride intake in drinking water at levels close to or above 4 mg/l is associated with dental
fluorosis and perhaps also bone fluorosis and/or weakening.; Damage to dental enamel recorded:
especially notable in young animals, which also showed atrophy of respiratory organs/tissues with
local oedema of bronchial mucosa. Older animals showed peribronchial hyperplasia. Animals around
1 year in age showed cavity formation in their bones.(Information on major hydrolysis product of the
registered substance (released rapidly on contact with water/moisture))(OECD Guideline 412)
- Carbon black : Mice were continuously fed various types of carbon black in massive quantities (10%
in diet) for 12 to 18 months. This led to no detectable changes from the normal in the organs and
tissues of the mice fed.
- Nickel; Raney nickel : In nickel plating industry, exposure to nickel containing vapors has been
reported to be assoc with asthma.
Aspiration Hazard : Not available