Cut Sheet

8882 High Gel, Part A 09/10/14
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Page 8 of 11
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test Result Exposure
Duration
EPOXIDIZED VEGETABLE OIL Ingestion Not toxic to female reproduction Rat NOAEL
1,000
mg/kg/day
1 generation
EPOXIDIZED VEGETABLE OIL Ingestion Not toxic to male reproduction Rat NOAEL
1,000
mg/kg/day
1 generation
EPOXIDIZED VEGETABLE OIL Ingestion Not toxic to development Rat NOAEL
1,000
mg/kg/day
1 generation
TOLUENE Inhalation Some positive female reproductive data
exist, but the data are not sufficient for
classification
Human NOAEL Not
available
occupational
exposure
TOLUENE Inhalation Some positive male reproductive data
exist, but the data are not sufficient for
classification
Rat NOAEL 2.3
mg/l
1 generation
TOLUENE Ingestion Toxic to development Rat LOAEL 520
mg/kg/day
during
gestation
TOLUENE Inhalation Toxic to development Human NOAEL Not
available
poisoning
and/or abuse
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test Result Exposure
Duration
TOLUENE Inhalation central nervous
system depression
May cause drowsiness or
dizziness
Human NOAEL Not
available
TOLUENE Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification
Human NOAEL Not
available
TOLUENE Inhalation immune system Some positive data exist, but the
data are not sufficient for
classification
Mouse NOAEL
0.004 mg/l
3 hours
TOLUENE Ingestion central nervous
system depression
May cause drowsiness or
dizziness
Human NOAEL Not
available
poisoning
and/or abuse
MALEIC ANHYDRIDE Inhalation respiratory irritation May cause respiratory irritation Human LOAEL
0.001 mg/l
occupational
exposure
Specific Target Organ Toxicity - repeated exposure
Name Route Target Organ(s) Value Species Test Result Exposure
Duration
EPOXIDIZED
VEGETABLE OIL
Ingestion liver | kidney and/or
bladder
Some positive data exist, but the
data are not sufficient for
classification
Rat NOAEL
1,250
mg/kg/day
2 years
TOLUENE Inhalation auditory system |
nervous system |
eyes | olfactory
system
Causes damage to organs
through prolonged or repeated
exposure
Human NOAEL Not
available
poisoning
and/or abuse
TOLUENE Inhalation respiratory system Some positive data exist, but the
data are not sufficient for
classification
Rat LOAEL 2.3
mg/l
15 months
TOLUENE Inhalation heart | liver | kidney
and/or bladder
Some positive data exist, but the
data are not sufficient for
classification
Rat NOAEL 11.3
mg/l
15 weeks
TOLUENE Inhalation endocrine system Some positive data exist, but the
data are not sufficient for
classification
Rat NOAEL 1.1
mg/l
4 weeks
TOLUENE Inhalation immune system Some positive data exist, but the
data are not sufficient for
classification
Mouse NOAEL Not
available
20 days