SDS

Large Hole Repair Compound 06/06/18
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Name
Route
Value
Glass Spheres
In Vitro
Some positive data exist, but the data are not
sufficient for classification
Titanium Dioxide
In Vitro
Not mutagenic
Titanium Dioxide
In vivo
Not mutagenic
Silica
In Vitro
Not mutagenic
2-Aminoisobutanol
In Vitro
Not mutagenic
2-Aminoisobutanol
In vivo
Not mutagenic
Carcinogenicity
Name
Route
Species
Value
Glass Spheres
Inhalation
Multiple
animal
species
Some positive data exist, but the data are not
sufficient for classification
Titanium Dioxide
Ingestion
Multiple
animal
species
Not carcinogenic
Titanium Dioxide
Inhalation
Rat
Carcinogenic
Silica
Not
Specified
Mouse
Some positive data exist, but the data are not
sufficient for classification
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name
Route
Value
Species
Test Result
Exposure
Duration
Silica
Ingestion
Not classified for female reproduction
Rat
NOAEL 509
mg/kg/day
1 generation
Silica
Ingestion
Not classified for male reproduction
Rat
NOAEL 497
mg/kg/day
1 generation
Silica
Ingestion
Not classified for development
Rat
NOAEL 1,350
mg/kg/day
during
organogenesi
s
2-Aminoisobutanol
Ingestion
Not classified for female reproduction
Rat
NOAEL 1,000
mg/kg/day
premating
into lactation
2-Aminoisobutanol
Ingestion
Not classified for male reproduction
Rat
NOAEL 1,000
mg/kg/day
37 days
2-Aminoisobutanol
Dermal
Not classified for development
Rat
NOAEL 300
mg/kg/day
during
gestation
2-Aminoisobutanol
Ingestion
Toxic to development
Rat
NOAEL 100
mg/kg/day
premating
into lactation
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name
Route
Target Organ(s)
Value
Species
Test Result
Exposure
Duration
2-Aminoisobutanol
Inhalation
respiratory irritation
Some positive data exist, but the
data are not sufficient for
classification
Mouse
NOAEL Not
available
Specific Target Organ Toxicity - repeated exposure
Name
Route
Target Organ(s)
Value
Species
Test Result
Exposure
Duration
Glass Spheres
Inhalation
respiratory system
Not classified
Human
NOAEL not
available
occupational
exposure
Titanium Dioxide
Inhalation
respiratory system
Some positive data exist, but the
data are not sufficient for
classification
Rat
LOAEL 0.01
mg/l
2 years
Titanium Dioxide
Inhalation
pulmonary fibrosis
Not classified
Human
NOAEL Not
available
occupational
exposure
Silica
Inhalation
respiratory system |
silicosis
Not classified
Human
NOAEL Not
available
occupational
exposure