Specifications

Maintenance
This section explains how to clean the Quest System after a synthesis has been
completed.
Perform three solvent washes (solvent delivery, agitation, drain) on each Reaction
Vessel Bank used for synthesis. Select a solvent that will dissolve any solids or
other residues that were generated during the synthesis. Fill the vessels about
314
full. Mix for 1 minute prior to draining the solvent. It may be desirable to run a
pattern of solvents through this wash process, depending on the type chemistry that
was run and the possible residues or particulates generated. If a pattern of solvents
are run through the system, do at least three wash iterations for each solvent.
After the last solvent wash, let the system drain for a couple of minutes to flush
residual solvent out of the Reactor Unit. You may want to choose a volatile solvent,
such as acetone, for this step.
With the drain valves still open, turn off the Drain gas (set valve to "Closed), and
turn on the Metered Gas. This will flush out the other common channel of the Upper
Manifold.
Place each Manifold Control Valve to the "Closed position. Close the drain valves.
Remove each luer plug and wipe clean with solvent if necessary. Examine each luer
hole for residue or particulates. If present, either rinse out the hole with a solvent
and
syringe,.or wipe clean with a cotton swab wetted with an appropriate solvent.
Raise the Upper Manifold and remove the reaction vessels. Use the pliers provided
to help with reaction vessel removal. Take care not to bump the tube inserts which
protrude from the Upper Manifold male reaction vessel fittings. Remove the
magnet mixers from the reaction vessels and clean. Discard the reaction vessels and
resin.
Examine the male reaction vessel fittings on the Upper Manifold and the Lower
Drain Manifold. Wi~e clean of anv residue or
articulates with a soft cloth and an
QUEST 210 User Manual
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