MSDS

Bayer Environmental Science
Material Safety Data Sheet
MSDS Number: 102000021105
BAYER ADVANCED ALL-IN-ONE ROSE & FLOWER CARE
READY-TO-USE GRANULES
MSDS Version 1.0
Page 6 of 8
None.
NTP
None.
IARC
None.
OSHA
None.
Reproductive toxicity
REPRODUCTION: Tebuconazole is not considered a primary reproductive
toxicant in rats. Reproductive effects (e.g., smaller litters) were observed at the
highest concentration but were considered secondary to maternal toxicity.
Imidacloprid was not a reproductive toxicant in a multi-generation study in rats.
Clothianidin is not considered a reproductive toxicant at non-maternally toxic
dose levels.
DEVELOPMENTAL TOXICITY: Tebuconazole is not considered a primary
developmental toxicant in laboratory animals. Developmental effects were
observed only at doses that caused maternal toxicity.
Imidacloprid is not considered a primary developmental toxicant in rats and
rabbits. Developmental effects were observed at doses that caused maternal
toxicity.
Clothianidin was not a primary developmental toxicant in rats and rabbits.
Developmental effects were observed in rabbits but were considered secondary
to maternal toxicity.
Neurotoxicity
Tebuconazole caused only transient neurobehavioral effects (e.g., decreased
motor activity) in acute, subchronic and/or developmental neurotoxicity studies in
rats.
Imidacloprid showed slight behavioral and activity changes only at the highest
dose tested in neurotoxicity studies in rats. There were no correlating
morphological changes observed in the neural tissues.
Clothianidin was not a neurotoxicant in acute, subchronic and developmental
neurotoxicity screening studies in rats.
Mutagenicity
Tebuconazole was not mutagenic or genotoxic in a battery of in vitro and in vivo
tests.
Imidacloprid was not mutagenic or genotoxic based on the overall weight of
evidence in a battery of in vitro and in vivo tests.
Clothianidin was not genotoxic based on the overall weight of evidence in a
battery of in vitro and in vivo tests.