User guide

Multiple attachment points
You can use R-groups that contain more than one attachment point, such as:
For this type of R-group, you must indicate in your table the attachment point order. If you have well-defined multiple
attachment points on your structure fragments, you can search for specific materials. This type of search is useful for
finding conformationally similar structures.
For example, assume you want to find compounds in figure A below but not compounds in figure B.
Figure 11.12: Multiple attachment points
By specifying the attachment point order, you can exclude the unwanted compounds.
To specify the attachment points order:
1. Draw the structure shown below
2. Create an alternative group box labeled “R1”.
ChemBioDraw 13.0
Chapter 11: Query structures 220 of 401