Operator`s manual

6
LightCycler® 480 Gene Scanning Software
Prologue
Trademarks
TrademarksIII
LIGHTCYCLER, LC, MAGNA PURE and HIGH PURE are trademarks of Roche.
Other brands or product names are trademarks of their respective holders.
Intended UseIV
With the LightCycler® 480 Gene Scanning Software, the user can detect heteroduplex
structures in DNA samples on the LightCycler® 480 Instrument. This assay requires only
routine PCR amplification of the sample followed by a simple, rapid High Resolution
Melting experiment in the presence of LightCycler® 480 High Resolution Melting Dye.
After the experiment, the software analyzes the shape of the melting curves and groups
those that are similar. Samples with known genotype can be included as melting standards
in the experiment, allowing the user to determine genotypes of unknown samples in the
analysis.
The LightCycler® 480 Gene Scanning Software is intended for general laboratory use in
combination with the LightCycler® 480 Instrument and LightCycler® 480 Software.
License Statements for the V
LightCycler
®
480 Gene Scanning Software
Parts of the Software used for the LightCycler 480 System are licensed from Idaho
Technology Inc., Salt Lake City, UT, USA.
This product is covered by one or more of U.S. 6,197,520, 6,303,305, 6,387,621, 6,503,720,
6,730,501 and corresponding claims in their non-U.S. counterparts, owned by Roche
Diagnostics GmbH and/or licensed from Idaho Technology, Inc.
This product is covered in-part by US 5,871,908 or any foreign equivalents, co-exclusively
licensed from Evotec OAI AG. The purchase price includes a license to practice the meth-
ods covered by US 5,871, 908 by using the product. Purchase of this product, however,
does not convey to the purchaser a license or right to
(i) commercially make, have made or sell reagents and/or kits, or
(ii) buy or use reagents and/or kits provided by a third party
used in conjunction with the product or any other thermocycler to practice the methods
covered by US 5,871,908 or any foreign equivalents.