093156 en MultivaporTM P-6/P-12 Operation Manual
Table of contents Table of contents 1 2 3 About this manual . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 1.1 Reference documents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 1.2 Trademarks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 1.3 Abbreviations . . . . . . . . . . . . . . . . .
Table of contents 4 5 4 Description of function . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28 4.1 Functional principle of the Multivapor . . . . . . . . . . . . . . . . . . . . . . . . . .28 4.1.1 Functional principle of the stand-alone unit . . . . . . . . . . . . . . . . . . . . . . .28 4.1.2 Functional principle of the Multivapor-Rotavapor edition . . . . . . . . . . . . . . .
Table of contents 6 7 8 9 10 11 5 Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .46 6.1 Settings at the Multivapor platform . . . . . . . . . . . . . . . . . . . . . . . . . . .46 6.1.1 Selecting a preset temperature . . . . . . . . . . . . . . . . . . . . . . . . . . . . .47 6.1.2 Changing/switching off the preset temperature . . . . . . . . . .
1 1 About this manual About this manual This manual describes the Multivapor P-6 and P-12 and provides all information required for its safe operation and to maintain it in good working order. It is addressed in particular to laboratory personnel and operators. NOTE The symbols pertaining to safety (WARNINGS and ATTENTIONS) are explained in chapter 2. 1.
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2 2 Safety Safety This chapter highlights the safety concept of the Multivapor and contains general rules of behavior and warnings from hazards concerning the use of the product. The safety of users and personnel can only be ensured if these safety instructions and the safetyrelated warnings in the individual chapters are strictly observed and followed, therefore, the manual must always be available to all persons performing the tasks described herein. 2.
2 2.4 Safety Safety warnings and safety signals used in this manual DANGER, WARNING, CAUTION and NOTICE are standardized signal words for identifying levels of hazard seriousness of risks related to personal injury and property damage. All signal words, which are related to personal injury are accompanied by the general safety sign.
2 Symbol Safety Meaning Explosive gases, explosive environment Harmful to life-forms Hot item, hot surface Explosive substance Device damage Inhalation of substances Flammable substances Fragile items / content Do not dispose of in household trash Wear protective mask Wear laboratory coat 10 Multivapor™ Operation Manual, Version E
2 Symbol Safety Meaning Wear protective goggles Wear protective gloves Additional user information Paragraphs starting with NOTE transport helpful information for working with the device / software or its supplementaries. NOTEs are not related to any kind of hazard or damage (see example below). NOTE Useful tips for the easy operation of the instrument / software. 2.
2 Safety NOTICE Risk of glass breakage by excessive strains. • • • • Mount all glassware parts without strains Check glassware for proper fixing regularly and readjust fixing points if necessary Do not use defective glassware Use the protective shield (optional) NOTICE Risk of instrument damage by wrong mains supply. • • 2.5.2 External mains supply must meet the voltage given on the type plate Check for sufficient grounding Other hazards ! WARNING Death or serious burns by flammable vapors.
2 2.5.4 Safety Safety elements Electronics • T he heating plate is equipped with an electronic over-temperature protection. It controls the temperature limit (the actual heating plate temperature may not exceed the set temperature by 2 °C for more than 2 minutes) and the function of the temperature sensor. • The heating plate is equipped with safety fuses. Parts in direct contact with the instrument • Combi clip for fixing the vacuum joint. • Ball joint clip for safe fixing of the receiving flask.
3 3 Technical data Technical data This chapter introduces the reader to the Multivapor and its main components. It contains technical data, requirements and performance data. 3.1 Scope of delivery Check the scope of delivery according to the order number. NOTE For detailed information on the listed products, see www.buchi.com or contact your local dealer. 3.1.
3 Technical data Table 3-1: Items included in the Basic configuration Product Order number Multivapor platform 220–240 V 100–120 V Crystal rack P-6 P-12 – – 11057500 11057505 Vacuum cover P-6 P-12 49773 49615 Tube adapters BUCHI Standard P-6 (6 pieces) BUCHI Standard P-12 (12 pieces) 11056598 11057082 Glassware BUCHI Standard vessel P-6 (6 pieces) BUCHI Standard vessel P-12 (25 pieces) 49774 49662 Transfer rack P-6 P-12 49250 49251 Sample preparation rack P-6 P-12 49783 49755 Condenser unit
3 Technical data Multivapor Rotavapor In contrast to the stand-alone configurations described before, this setup is connected to an already installed rotary evaporator. Delivery therefore includes the Multivapor with a Rotavapor set to combine it with the condenser of the rotary evaporator.
3 3.1.2 Technical data Ordering matrix In this section the items accessible by the ordering matrix are listed. NOTE The standard plastic material is PETP, however, for very harsh conditions such as trifluoric acid (TFA) PEEK is available as a highly resistant alternative. In this case configure the system without evaporation unit and tube adapters (position „00“ in the matrix section „evaporation unit“) and order the corresponding items separately as accessory.
3 Technical data Order number: MP x x 1 x x x x x Protective shield Product Order number Protective shield P-6, P-12 48784 Order number: MP x x x x x x Evaporation unit, tube adapter, glassware Product 01: Configuration with evaporation unit (i.e. crystal rack and vacuum cover), set of tube adapters for BUCHI’s standard sample tubes, preparation/transfer rack, set of BUCHI’s standard sample tubes (ø 60 mm for P-6, ø 25 mm for P-12).
3 Technical data Order number: MP x x x x x x Condenser assembly, P+G coated Product Order number Type S condenser for tap water or a recirculating chiller.
3 Technical data Order number: MP x x x x x x x Vacuum solution Product Order number Comprises a Woulff bottle to trap particles and droplets before the vacuum inlet. V -700, V-855 with secondary condenser according to the type of the primary condenser 3.1.
3 Technical data Table 3-5: Standard accessories (cont.
3 Standard accessory glassware 1 2 3 4 6 5 8 7 Fig. 3.1: Overview over the available BUCHI glassware and the corresponding adapters P-12 Sample tubes available from BUCHI P-6 3.1.
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3 Technical data Table 3-8: Optional accessories (cont.) 3.
3 Technical data Table 3-10: Range of application for the O-rings of the conical adapters EPDM FKM FKKM PEEK PET(P) PFA PTFE Acetaldehyde B D A A A A A Acetic acid A B A A A A A Acetic acid anhydride B D A A A A A Acetone A D A A B A A Benzene D A A A A A A Butanol B A A A B A A Chloroform D A A A B A A Diethyl ether C C A A A A A Dimethylformamide A - A A B A A Dimethylbenzene (Xylol) D A A A A A A Dioxane B - A A
3 3.3 Technical data Technical data overview Table 3-11: Technical data Dimensions ( W×H×D) 270×400×400 mm Weight P-6: 22 kg, P-12: 21 kg Connection voltage 100 – 120 or 220 – 240 VAC ± 10% Fuse T 3.1 A L 250 V (220–240 V) T 6.3 A L 250 V (100–120 V) Power consumption max.
3 3.4 Technical data Solvent table Table 3-12: Solvent table Solvent Formula Molar mass Evaporation energy Boiling point Density Vacuum in mbar for in g / mol in J / g at 1013 mbar in g / cm3 boiling point at 40 °C 56 0.790 556 Acetone C3H6O n-Amylalcohol, n-pentanol C5H12O 88.1 595 37 0.814 11 C6H6 78.1 548 80 0.877 236 Benzene 58.1 553 n-Butanol, tert-butanol C4H10O 74.1 620 118 0.810 25 2-Methyl-2-propanol C4H10O 74.1 590 82 0.
4 4 Description of function Description of function This chapter explains the basic principle of the Multivapor P-6 and P-12 and provides a functional description of the assemblies. 4.1 Functional principle of the Multivapor The Multivapor is a 6 or 12 position parallel evaporator for simultaneous evaporation of up to 6×150 mL or 12×30 mL sample volume, referred to as Multivapor P-6 or Multivapor P-12, respectively.
4 Description of function a Evaporation area The solvent is heated by means of a heating plate. Horizontal orbital movement of the heating plate results in a thorough vortex of the mixture within the test tubes. Thus, the solvent surface is increased which in turn leads to a higher evaporation rate and reduction of boiling retardation. b Cooling area Each sample is individually connected to the vacuum cover with glassware specific adapters.
4 Description of function condenser cannot cope with the amount of vapor produced. During operation of the Multivapor, the Rotavapor side has to be closed using an empty evaporation flask e. 4.1.3 Controls of the Multivapor (stand-alone) a Main switch b Temperature display c Knob for temperature regulation d Knob for rotational speed e Holder for the vacuum cover 5 1 2 3 4 Fig. 4.4: Overview of the Multivapor controls 4.1.
4 4.1.5 Description of function Rear connections of the Multivapor a Mains supply b Main fuse 2 1 Fig. 4.6: Rear connection of the Multivapor 4.2 Multivapor platform The platform is available with a 220–240 V and a 100–120 V power supply. The temperature and orbital movement of the heating plate are individually adjusted via the corresponding control knobs. The temperature is limited to 95 °C to prevent evaporation of water which is used as heat transfer medium.
4 4.3 Description of function Crystal rack The crystal rack a is fixed onto the heating plate and operates as a heat transition between the heating plate and the sample tubes. It comprises 6 or 12 glass cylinders accommodated circularly to provide full supervision. A level indication designates the optimal filling level for water, which serves as the heating medium.
4 4.5 Blank adapters (optional) Fig. 4.10: Blank adapters 4.6 Description of function If less than the maximum number of samples are being evaporated, the vacant positions need to be occupied either with empty sample tubes or with the optional blank adapters. These adapters consist of a closed bottom side but the same outer dimensions as the standard adapters. It is not necessary to distribute the samples equally across the crystal rack.
4 4.8 Description of function Sample transfer plate As the test tubes are tightly fixed to the transfer plate, the whole assembly is transferred at once into the crystal rack. This allows a preceding equilibration of the instrument. Fig. 4.13: Simultaneous sample transfer using the transfer plate 4.9 Vacuum cover 2 1 The samples are sealed with the vacuum cover a via the adapters b. The cover serves as vacuum manifold collecting the vapor from each sample individually in grooved channels.
4 4.10 Description of function Protective shield (optional) The protective shield protects the user from splashes of hot medium and debris from the sample tubes in the case of implosion or explosion. Fig. 4.15: Protective shield 4.11 Condensation (optional) There are two types of condensers available. Type C condensers (left) are used with dryice/acetone and type S condensers (right) are connected to tap water or a recirculating chiller. Both are equipped with a P+G coating to provide maximum safety.
4 4.12 Description of function High-boiling solvents - Woulff bottle (optional) To prevent boiling retardation and for highboiling solvents which tend to condense in the vacuum tube as well as for solvents which tend to foam an optional solvent reservoir – the socalled Woulff bottle – can be fixed at the rear of the instrument. The vapor is then first transferred from the cover to the bottle and then further to the condenser assembly. Fig. 4.17: Woulff bottle installed 4.
4 4.14 Description of function Connection to a rotary evaporator (optional) Fig. 4.19: A resource-sharing combination of the condenser, the vacuum pump and the controller with both the Rotavapor and the Multivapor In addition to the stand-alone unit, the Multivapor can be used in combination with a rotary evaporator. The vapor is then first transferred to the condenser assembly of the Rotavapor with the help of the T-piece. The vacuum is generated by the vacuum pump and regulated by the controller.
5 5 Putting into operation Putting into operation This chapter describes the installation of the Multivapor and gives instructions on initial start-up. NOTE Inspect the instrument for damages during unpacking. If necessary, prepare a status report immediately to inform the postal company, railway company or transport company. Keep the original packaging for future transport. 5.1 Installation site Place the instrument on a stable, horizontal surface and consider the maximum product dimensions.
5 5.3 Commissioning the Multivapor basic instrument 5.3.1 Commissioning the crystal rack Putting into operation Fig. 5.21: Installation of the crystal rack onto the heating plate Remove any particles from the heating plate and the bottom side of the crystal rack. Place the rack onto the heating plate with the indentation to the front.
5 5.3.2 Putting into operation Assembling the Woulff bottle (optional) Fig. 5.22: Assembling the Woulff bottle 5.3.3 1 Fix the Woulff bottle holder on the bottom of the instrument by replacing the existing screws with the provided longer screws. 2 Fix the Woulff bottle holder on the rear side of the instrument by replacing the existing screws with the provided longer screws. Add the cover of the Woulff bottle from above to the holder.
5 5.4 Putting into operation Glass assembly NOTICE Risk of glass breakage by excessive strains. • • • • 5.4.1 Mount all glassware parts without strains Check glassware for proper fixing regularly and readjust fixing points if necessary Do not use defective glassware Use the protective shield (optional) Type S and type C condenser Install the condenser assemblies on the provided support or on a stable laboratory rod ensuring that the stand base is oriented in the direction of the condenser.
5 5.5 Tube connections 5.5.1 Cooling water Putting into operation When connecting the white cooling water tubes (silicon), consider the following: • • • • Use GL-14 tube clips. The tubes used must all have the same inner diameter (approximately 6 mm). For safety reasons, secure the tubes with commercial tube pivoting clamps or cable binders. To save cooling water and/or reduce the temperature of the coolant, a recirculating chiller like the F-100/F-108 is recommended.
5 5.5.2 Putting into operation Vacuum tubes When establishing the vacuum tube (red rubber) connections proceed as follows: • • • • Use GL-14 tube clips. The tubes used must all have the same inner diameter (approximately 5 mm). Keep vacuum tubes as short as possible. When operating with the Vacuum Controller V-850/V-855 and the Vacuum Pump V-700/V-710 connect a Woulff bottle between the vacuum source and the Multivapor.
5 5.6 Putting into operation Commissioning the Multivapor-Rotavapor edition The T-piece is inserted between the condenser and the receiving flask of the rotary evaporator and fixed with the clip. The vacuum tube is connected to the SVL 22 joint of the T-piece. Fig. 5.28: Commissioning the Multivapor-Rotavapor edition NOTE As the system has to be closed in order to generate a vacuum, the vapor duct on the rotary evaporator must be sealed with an empty flask during operation. 5.
5 Putting into operation the corresponding seals. The adapter seals have to be exchanged regularly. The corresponding spare parts are listed in section 10.3. NOTE Overtightening the lock nuts on the conical adapters of the vacuum cover and sample tubes will scarcely remedy a leak problem, but would decrease the lifetime of the parts. The problem is more readily solved by checking the quality of the corresponding seals, i.e. the adapter seals and/or the conical O-rings.
6 6 Operation Operation This chapter explains the operating elements and possible operating modes. It gives instructions on how to operate the Multivapor properly and safely. 6.1 Settings at the Multivapor platform Variable parameters of the instrument are the temperature and rotational speed of the horizontal movement of the heating plate. NOTICE Risk of glass breakage by excessive strains. • • • • Mount all glassware parts without strains.
6 6.1.1 Operation Selecting a preset temperature A preset temperature setting ensures that the heating bath temperature cannot be changed either accidentally or deliberately during the evaporation process. To switch to the preset mode, proceed as follows: • • • • Switch off the instrument. Turn the adjusting knob to the 95 °C (max) position. Switch on the instrument. The set temperature setting flashes on the display. Turn the knob to the desired set temperature, e.g.
6 6.2 Sample preparation 6.2.1 Heating up the instrument Operation Distilled water is added to each glass cylinder on the crystal rack to transfer the heat from the heating plate to the sample tube. Equal amounts of water must be added to each cylinder to provide a uniform heat transfer. A level indication designates the optimum volumes depending on the type of sample tube. Turn on the heating as soon as each position is filled. It takes approximately 20 min to equilibrate the system, i.e.
6 Operation • Screw the adapter onto the tube. • P lace the sample tube into the transfer plate. Make sure that it snaps in place. • O ccupy all positions or use the blank adapters instead (optional). • T ransfer the whole assembly at once into the pre-heated crystal-rack. • Close the vacuum cover. • T ighten the vacuum cover using the quick lock. Fig. 6.
6 6.3 Operation Selecting the distillation conditions To achieve optimal distillation conditions, the distillation energy supplied by the heating platform must be removed by the condenser. To ensure this, operate the instrument according to the following general rule: 25 °C 20 °C Heating medium: 55 °C Vapor: 30 °C Coolant: max. 10 °C How are these conditions achieved? • Set the temperature of the instrument to 55 °C. • Use a recirculating chiller to set the temperature of the coolant to max.
6 6.4 Operation Distillation Before operating the system, the following conditions must be fulfilled: • All electrical connections are established correctly. • All vacuum and coolant connections are established correctly. The latter being secured with cable binders. • All seals are inserted correctly. • Water is filled in according to the level indication. To start operating the system proceed as follows: • • • • • • • • • • Switch on the instrument. Set the temperature (recommended: 50 – 80 °C).
6 6.5.2 Operation Pressure gradients (V-855) Setting the pressure manually to the boiling point involves the risk of boiling retardation. To minimize this risk, it is strongly recommended to program a pressure gradient that slowly converges to the optimized ultimate vacuum. This is achieved as follows: • Select the Gradient mode. • Program the first step. • P rogram additional steps and terminate the programming by selecting “Yes”.
6 Operation tend to foam or splash. A preceding terrace at high pressure for approx. 10 min usually significantly reduces the risk of splashing or foaming. 6.5.3 Automatic distillation (V-855) 2 1 The method of choice to evaporate even complex sample mixtures automatically is the EasyVac mode, implemented in the Vacuum Controller V-855. The EasyVac algorithm is based on relative pressure changes over time and therefore requires no additional accessory for operation.
6 Operation heating plate and the ambient temperature. 6.7 When the distillation “dies out” When the distillation “dies out”, i.e. the process draws to a close, back evaporation may occur. In this event appropriate actions are either to interrupt the distillation in order to empty the receiving flask or to keep the solvent at a low temperature (see also section 6.5.2). A convenient accessory for the latter is the refrigerated receiver.
7 7 Maintenance Maintenance This chapter provides instructions on all required maintenance to keep the instrument in good working condition. ! WARNING Death or serious burns by electric current at cleaning. • • • 7.1 Switch off the instrument Disconnect the power cord and prevent unintentional restart Wait until the instrument is completely dry before reconnecting to mains Housing NOTICE Risk of instrument damage by using solvents as cleaning agents.
7 7.3.2 Maintenance Replacing the tube adapter seals 1 2 a Use the Multivapor tool for removing the insert of the adapter and for changing the gasket. b Replace the gasket if damaged or broken, and reassemble. Fig. 7.39: Replacing the tube adapter seals 7.3.3 Replacing the conical adapter O-rings Fig. 7.40: Replacing the conical adapter O-rings The O-ring of the conical adapters may become either chemically or physically damaged under harsh conditions or upon intensive regular use respectively.
7 7.3.4 Maintenance Cleaning the vacuum cover and replacing the corresponding O-rings NOTICE Risk of component damage. • • Close the screws at the vacuum cover hand-tight. Avoid overtightening. Clean the vacuum cover regularly by rinsing it with water or ethanol through the holes of the conical adapters. Unmount the cover only in case of severe contamination. Use the optional PE frits to protect the cover from any possible splashes (see also chapter 4.6). Fig. 7.41: Cleaning the vacuum cover 7.
7 Maintenance To remove the crystal rack for cleaning, proceed as follows: 1 Pull and hold the locking device. 2 Turn the rack a little clockwise and let the locking device go. Turn the rack further clockwise, until the lockingdevice snaps into place. The rack can now be taken away from the instrument.
7 Maintenance NOTE Screw the lid only hand-tight as overtightening may break the glass cylinders. Test the tightness of the system with water prior to the installation onto the heating plate. 7.5 Glass components To prolong the lifetime of the glass components rinse them regularly with water and a commercial cleaning agent (e.g. mild soap solution). NOTE It is recommended to clean all glass components manually. Use an alkaline cleaner to remove dirt, e.g. algae adhering to the condenser coil.
8 8 Troubleshooting Troubleshooting The following chapter describes how to resume operation of the instrument in the event of any minor problem. It will list some possible occurrences, their probable cause and suggests how to remedy the problem. The troubleshooting table below lists possible malfunctions and errors of the instrument and describes operator enabled courses of action to correct some of those problems by him or herself.
8 Troubleshooting Table 8-1: General malfunctions and their remedy Malfunction Possible cause Remedy Distillation stopped despite not being Back evaporation of the distillate dried out completely (especially for solvent mixtures) Malfunction in distillation procedure which is not exactly defined (e.g. sudden cooling, heat flow too low, etc.
9 9 Shutdown, storage, transport and disposal Shutdown, storage, transport and disposal This chapter instructs on how to shut down the instrument, how to pack it for storage or transport and specifies the storage and shipping conditions. 9.1 Storage and transport Store the instrument at a dry place. Store and transport the instrument in its original packaging. ! WARNING Death or serious poisoning by contact or incorporation of harmful substances. • • • • • • 9.
9 9.3 Shutdown, storage, transport and disposal Health and safety clearance form Declaration concerning safety, potential hazards and safe disposal of waste, e.g. used oil. Safety and health of our staff, laws and regulations regarding the handling of dangerous goods, occupational health and safety regulations, safety at work laws and regulations regarding safe disposal of waste, e.g.
10 10 Spare parts Spare parts This chapter lists spare parts, accessories, and optional extras, including all of the relevant order information for ordering from BUCHI. Always state the product designation and part number when ordering any spare parts. Use only genuine BUCHI consumables and spare parts for maintenance and repair to ensure optimum system performance and reliability. Prior written permission of the manufacturer should be obtained before any modifications are made to the spare parts used.
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10 Spare parts Table 10-3: Evaporation unit P-12 11057259 66 Product Order number Quick lock nut 11057259 Vacuum cover O-ring, small (EPDM) 49677 Vacuum cover O-ring, large (EPDM) 49676 Vacuum cover adapter SVL 22 (PETP) 49673 Vacuum cover adapter SVL 22 (PEEK) 48850 Set of 12 conical adapters (PETP) 48868 Set of 12 conical adapters (PEEK) 48847 Set of 12 adapter O-rings (EPDM) 48867 Set of 12 adapter O-rings (FKM) 48827 Set of 12 adapter O-rings (FFKM) 48849 Support rod 49654 Gl
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10 10.4 Spare parts Condenser assemblies Table 10-6: Condenser assembly type S Product Order number Set of 5 GL-14 blind caps 40624 Set of 4 bent GL-14 tube connections 40295 Silicon water tube, 1.5 m, ø 6/9 mm 43940 Water tube temperature insulation, 1.
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10 Spare parts Table 10-10: Sample vessels Product Order number Set of 25 round bottom BUCHI P-12 sample 49662 vessels with screw cap (GPI 24-400, working volume 30 mL, ø 27 mm, L = 145 mm) Set of 72 flat bottom PSE/ASE tubes (GPI 24-400, working volume 30 mL) 49535 Set of 50 test tubes OD 25 (25×150 mm) 38469 Set of 100 test tubes OD 20 (20×150 mm) 42845 Set of 100 test tubes OD 16 (16×130 mm) 38543 Set of 6 round bottom BUCHI P-6 sample vessels with screw cap (GL 45, working volume 150 mL) 49
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10 Spare parts Table 10-15: Vacuum solutions Product Order number Vacuum Controller V-850 47231 Vacuum Controller V-855 47232 Valve unit for combination of the Vacuum Controller V-850/V-855 with non-BUCHI vacuum pumps 47160 Table 10-16: Recirculating chiller 72 Product Order number F-100, 230 V; 50/60 Hz (1400 W) 11056460 F-100, 115 V; 50/60 Hz (1400 W) 11056461 F-108, 230 V; 50/60 Hz (800 W) 11056464 F-108, 115 V; 50/60 Hz (800 W) 11056465 Multivapor™ Operation Manual, Version E
11 11 Declarations and requirements 11.1 FCC requirements (for USA and Canada) Declarations and requirements English: This equipment has been tested and found to comply with the limits for a Class A digital device, pursuant to both Part 15 of the FCC Rules and the radio interference regulations of the Canadian Department of Communications. These limits are designed to provide reasonable protection against harmful interference when the equipment is operated in a commercial environment.
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Multivapor P-6/P-12 Operation Manual Quality in your hands Find your BUCHI Contacts: BÜCHI Labortechnik AG CH – 9230 Flawil 1 T +41 71 394 63 63 F +41 71 394 65 65 buchi@buchi.com www.buchi.com BUCHI Italia S.r.l. IT – 20010 Cornaredo (MI) T +39 02 824 50 11 F +39 02 57 51 28 55 italia@buchi.com www.buchi.it BUCHI Hong Kong Ltd. HK – Central T +852 2389 2772 F +852 2389 2774 china@buchi.com www.buchi.com.cn Nihon BUCHI K.K. JP – Tokyo 110-0008 T +81 3 3821 4777 F +81 3 3821 4555 nihon@buchi.com www.