User guide

ANNEX 3
88
POST-OCCLUSION BOLUS
MAN 01/06/USA/p CRONO FIVE 11.10
When the occlusion alarm signal is triggered, the pump has built up a cer -
tain overpressure in the administration line(s), which has to be eliminated to
avoid an accidental post occlusion bolus that could result in serious injury or
death to the patient. The size of a post-occlusion bolus for Crono Five in
combination with an infusion set with 27G needle, 80 cm lenght with very
stiff lining is about 0.4 ml.
Post-occlusion bolus may deviate from the information in this user guide
depending on which type of extension set, tubing and access devices that
are used for the administration of a medication.
CAUTION
The size of a post-occlusion bolus can increase if there is air in the line,
when other catheter sizes, filters and extension set tubing with softer mate -
rials are used, or when the lines from the pump are connected to other
access devices.
Patients, who are likely to be adversely affected (serious injury or death) by
an accidental release of the post-occlusion bolus, should not eliminate the
bolus before having instructions how to do the elimination correctly or be
trained to eliminate the post-occlusion bolus correctly themselves before the
drug delivery is resumed.