MSDS
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Revision Number: %%revision_number%%
Revision Date: March 10, 2006
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Chevron TECHRON® Concentrate
PLUS
MSDS : 14397
SECTION 11 TOXICOLOGICAL INFORMATION
IMMEDIATE HEALTH EFFECTS
Eye Irritation: The eye irritation hazard is based on evaluation of data for similar materials or product
components.
Skin Irritation: The skin irritation hazard is based on evaluation of data for similar materials or product
components.
Skin Sensitization: No product toxicology data available.
Acute Dermal Toxicity: The acute dermal toxicity hazard is based on evaluation of data for similar
materials or product components.
Acute Oral Toxicity: The acute oral toxicity hazard is based on evaluation of data for similar materials
or product components.
Acute Inhalation Toxicity: The acute inhalation toxicity hazard is based on evaluation of data for
similar materials or product components.
ADDITIONAL TOXICOLOGY INFORMATION:
COMPONENT: Light Aromatic Solvent Naphtha (CAS 64742-95-6, also described as High-Flash
Aromatic Naphtha, Type I, as defined by ASTM D-3734). GENETIC TOXICITY: No evidence of genetic
toxicity was observed in the following tests: Salmonella typhimurium reverse mutation assay (Ames test),
in vitro Chinese Hamster Ovary (CHO) cell HGPRT mutation assay, in vitro Chinese Hamster Ovary
(CHO) cell chromosomal aberration assay, in vitro Chinese Hamster Ovary (CHO) cell sister chromatid
exchange assay, and in vivo rat bone marrow chromosome aberration assay. SUBCHRONIC
TOXICITY: In a 13-week rat inhalation study using dose levels of 0, 100, 500, and 1500 ppm for 6
hours/day, 5 days/week, no target organ toxicity including neurotoxicity was observed at any dose level.
Slight general systemic toxicity (decreased body weight gain) was observed at 1500 ppm.
This product contains Stoddard solvent, a mixture of straight and branched-chain paraffins, naphthenes
and aromatic hydrocarbons. Based on studies of Stoddard solvent sample 85-01 sponsored by the
American Petroleum Institute, the acute dermal LD50 was found to be >3.0 g/kg and the acute oral LD50
was found to >5.0 g/kg. Acute inhalation toxicity tests showed a no observable effect level for inhalation
of Stoddard solvent at 4.0 mg/l, with eye irritation and slight loss of coordination at 8 mg/l, and tremors,
CNS depression and death within 7.5 hours of exposure to 10 mg/l. In a 28-day dermal study sponsored
by the API, moderate skin irritation occurred at 200 mg/kg, with moderate to severe irritation above 1000
mg/kg. The API also determined the primary dermal irritation index to be 4.5, and the primary eye
irritation index to be 0.0 at 24 hours. In human sensory response tests, exposure to Stoddard solvent at
0.60 mg/l caused mild eye and nose irritation after 30 minutes, with increased blink rate and eye irritation
at 2.4 mg/l, and eye irritation and tearing at 2.7 mg/l. No significant effects on psychomotor performance
were noted.
DEVELOPMENTAL TOXICITY: In a mouse inhalation study using dose levels of 0, 100, 500, and 1500
ppm for 6 hours/day on gestation days 6-15, no signs of maternal toxicity or developmental toxicity were
observed at 100 ppm. At 500 ppm, maternal toxicity (decreased body weight gain) and developmental
toxicity (decreased fetal body weight) were observed. Severe maternal toxicity (44% mortality,
decreased body weight gain, clinical signs of toxicity) and developmental toxicity (decreased number of
live fetuses per litter, increased post-implantation losses per dam, decreased fetal body weights, delayed
ossification, cleft palate) were observed at 1500 ppm. In a rat inhalation study using dose levels of 600,
1000, and 2000 mg/m3 for 24 hours/day on gestation days 7-15, signs of maternal toxicity (decreased
body weight gain) were observed at all dose levels. At 600 mg/m3, no signs of fetal or developmental
toxicity were observed. Signs of fetal toxicity (decreased male fetal body weight) and developmental
toxicity (delayed ossification) were observed at 1000 and 2000 mg/m3. REPRODUCTIVE TOXICITY: In
a rat 3-generation inhalation study using dose levels of 0, 100, 500, and 1500 ppm for 6 hours/day, 5
days/week, no signs of general systemic or reproductive toxicity were observed at 100 ppm. At 500
ppm, slight parental toxicity (decreased body weight gain) and postnatal toxicity (decreased pup body