Technical data

Contents
1. General Information 1
1.1. Introduction ......................................................................................................1
1.2. Areas of application .........................................................................................2
1.3. Technical data of freeze dryer ALPHA 1-4 LSC / ALPHA 2-4 LSC.................3
1.4. Standards and regulations...............................................................................6
1.5. Safety instructions............................................................................................6
1.5.1. CAUTION! Disconnect the mains plug!..............................................6
1.5.2. CAUTION! Solvents!...........................................................................6
1.5.3. ADVICE! Cleaning and Maintenance of the Unit!...............................6
1.5.4. WARNING! Freezing of limbs to surfaces!.........................................6
1.5.5. NOTE! Transport instructions!............................................................7
1.6. Prohibited freeze drying processes .................................................................8
2. General Information on Freeze Drying 9
2.1. General Information on Freeze Drying ............................................................9
2.2. Preparation.....................................................................................................12
2.3. Freezing .........................................................................................................12
2.4. Main drying.....................................................................................................13
2.5. Final drying.....................................................................................................17
2.6. End of drying and aeration.............................................................................18
2.7. Defrosting.......................................................................................................18
3. Description of the Freeze Drying Processes 19
3.1. Freezing and drying inside the ice condenser chamber
(process A) on a temperature-controlled shelf...............................................19
3.2. Separate freezing and drying outside the ice condenser chamber
(process B) on temperature-controlled shelves.............................................20
3.3. Separate freezing and drying outside the ice condenser chamber
(process B) with sealing device .....................................................................22
3.4. Separate freezing and drying of liquids in flasks (process B)........................23
3.5. Separate freezing and drying of liquids in ampoules (process B) .................24
4. Installation and Commissioning of the Unit 25
4.1. Site of installation...........................................................................................25
4.2. Mains power...................................................................................................26
4.3. Fuses on site..................................................................................................26
4.4. Checking the ground connection ...................................................................26
4.5. Aeration..........................................................................................................26
4.6. Condensate and defrosting water..................................................................26
4.7. Vacuum pump exhaust gases........................................................................27
4.8. Initial start-up..................................................................................................28
4.8.1. Functional components and control elements..................................28
4.8.2. Vacuum sensor, vacuum pump and pressure control valve
connection.........................................................................................29
4.8.3. Installation of accessory components ..............................................33
4.8.4. Preparations for freeze-drying..........................................................37
4.8.5. Power-on ..........................................................................................37
Operating Manual Freeze Dryer ALPHA 1-4 LSC / ALPHA 2-4 LSC Contents • iii