SDS

SAFETY DATA SHEET
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Genetron® AZ-20 (R-410A)
000000009881
Version 1.0 0 Issuing date 02/01/2012 Revision Date 02/01/2012 Print Date 07/24/2013
9/12
: Cell type: Human lymphocytes
Result: negative
: Cell type: Chinese Hamster Ovary Cells
Result: negative
: Cell type: Human lymphocytes
Result: negative
Method: Mutagenicity (in vitro mammalian cytogenetic test)
: Test Method: Chromosome aberration test in vitro
Result: negative
Germ cell mutagenicity
Difluoromethane : Species: mouse
Cell type: Bone marrow
Method: Mutagenicity (micronucleus test)
Result: negative
Teratogenicity
Pentafluoroethane : Species: rabbit
Application Route: Inhalation exposure
NOAEL,Teratog: 50,000 ppm
NOAEL,Maternal: 50,000 ppm
Note: Did not show teratogenic effects in animal experiments.
Species: rat
Application Route: Inhalation exposure
NOAEL,Teratog: 50,000 ppm
NOAEL,Maternal: 50,000 ppm
Note: Did not show teratogenic effects in animal experiments.
Difluoromethane : Species: rat
Dose: NOEL - 50,000 ppm
Note: Did not show teratogenic effects in animal experiments.
Species: rabbit
Dose: NOEL - 50,000 ppm
Note: Did not show teratogenic effects in animal experiments.
Further information
Acute toxicity : Vapours are heavier than air and can cause suffocation by
reducing oxygen available for breathing. Rapid evaporation of
the liquid may cause frostbite. May cause cardiac arrhythmia.
12. ECOLOGICAL INFORMATION