Owner`s manual

Product Name: DOWFROST* HD Heat Transfer Fluid, Dyed Issue Date: 08/12/2010
Page 5 of 7
Acute Toxicity
Ingestion
LD50, Rat, female
> 20,300 mg/kg
Dermal
For the major component(s): LD50, Rabbit
> 20,000 mg/kg
Inhalation
For the major component(s): No deaths occurred following exposure to a saturated atmosphere.
LC50, 8 h, Vapor
,
Rat
4.1 mg/l
Eye damage/eye irritation
May cause slight temporary eye irritation. Corneal injury is unlikely.
Skin corrosion/irritation
Prolonged contact is essentially nonirritating to skin. Repeated contact may cause flaking and
softening of skin.
Sensitization
Skin
For the major component(s): Did not cause allergic skin reactions when tested in humans.
Respiratory
No relevant information found.
Repeated Dose Toxicity
In rare cases, repeated excessive exposure to propylene glycol may cause central nervous system
effects.
Chronic Toxicity and Carcinogenicity
Similar formulations did not cause cancer in laboratory animals.
Developmental Toxicity
For the major component(s): Did not cause birth defects or any other fetal effects in laboratory
animals.
Reproductive Toxicity
For the major component(s): In animal studies, did not interfere with reproduction. In animal studies,
did not interfere with fertility.
Genetic Toxicology
In vitro genetic toxicity studies were negative. For the major component(s): Animal genetic toxicity
studies were negative.
12. Ecological Information
ENVIRONMENTAL FATE
Movement & Partitioning
For the major component(s): Bioconcentration potential is low (BCF less than 100 or log Pow less
than 3). Potential for mobility in soil is very high (Koc between 0 and 50).
Persistence and Degradability
For the major component(s): Material is readily biodegradable. Passes OECD test(s) for ready
biodegradability.
ECOTOXICITY
For the major component(s): Material is practically non-toxic to aquatic organisms on an acute basis
(LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested).
13. Disposal Considerations
DO NOT DUMP INTO ANY SEWERS, ON THE GROUND, OR INTO ANY BODY OF WATER. All
disposal practices must be in compliance with all Federal, State/Provincial and local laws and
regulations. Regulations may vary in different locations. Waste characterizations and compliance with
applicable laws are the responsibility solely of the waste generator. AS YOUR SUPPLIER, WE HAVE