SDS
Product name: FILL AND SEAL™ Expanding Foam Sealant 12oz
HC ES 12ct
Issue Date: 01/19/2016
Page 10 of 18
Liver.
Carcinogenicity
Lung tumors have been observed in laboratory animals exposed to respirable aerosol droplets of
MDI/Polymeric MDI (6 mg/m3) for their lifetime. Tumors occurred concurrently with respiratory
irritation and lung injury. Current exposure guidelines are expected to protect against these effects
reported for MDI.
Teratogenicity
In laboratory animals, MDI/polymeric MDI did not cause birth defects; other fetal effects occurred only
at high doses which were toxic to the mother.
Reproductive toxicity
Based on information for component(s): May cause harm to breastfed babies.
Mutagenicity
In vitro genetic toxicity studies were negative for component(s) tested. Genetic toxicity data on MDI
are inconclusive. MDI was weakly positive in some in vitro studies; other in vitro studies were negative.
Animal mutagenicity studies were predominantly negative.
Aspiration Hazard
Based on physical properties, not likely to be an aspiration hazard.
Carcinogenicity
Component
List
Classification
Paraffin waxes and
Hydrocarbon waxes,
chlorinated
IARC
Group 2B: Possibly carcinogenic to
humans
US NTP
Reasonably anticipated to be a human
carcinogen
12. ECOLOGICAL INFORMATION
Ecotoxicological information appears in this section when such data is available.
Toxicity
Diphenylmethane Diisocyanate, isomers and homologues
Acute toxicity to fish
The measured ecotoxicity is that of the hydrolyzed product, generally under conditions
maximizing production of soluble species.
Material is practically non-toxic to aquatic organisms on an acute basis
(LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested).
Based on information for a similar material:
LC50, Danio rerio (zebra fish), static test, 96 Hour, > 1,000 mg/l, OECD Test Guideline 203 or
Equivalent
Acute toxicity to aquatic invertebrates
Based on information for a similar material:
EC50, Daphnia magna (Water flea), static test, 24 Hour, > 1,000 mg/l, OECD Test Guideline
202 or Equivalent