Safer Choice Standard

GAF SDS # 1008A
Page 2 of 7
INGESTION:
This product is not intended to be ingested. If ingested, it may
cause temporary irritation to the gastrointestinal (digestive)
tract.
INHALATION:
May cause irritation to the respiratory tract.
ACUTE HEALTH HAZARDS:
None known.
CHRONIC HEALTH HAZARDS:
Studies in humans have found that exposure to respirable
crystalline silica (quartz) can cause silicosis, a fibrosis
(scarring) of the lungs. Silicosis is a serious and irreversible
disease; it may be progressive even after exposure has
ceased; it can lead to disability and death. Human studies
also have found that silicosis is a risk factor for tuberculosis,
and that occupational exposure to respirable crystalline silica
is associated with chronic obstructive pulmonary disease,
including bronchitis and emphysema. Some studies show
excess numbers of cases of scleroderma, connective tissue
disorders, lupus, rheumatoid arthritis, chronic kidney diseases
and end-stage kidney disease in workers exposed to
respirable crystalline silica.
CARCINOGENICITY:
NIOSH has concluded that the collective data from human,
animal, genotoxicity and exposure studies provide sufficient
evidence that roofing asphalt fumes are a potential
occupational carcinogen.
Occupational exposure to respirable crystalline silica is
classified as a known carcinogen in humans. IARC has
determined that respirable crystalline silica is carcinogenic to
humans (Group 1), based on findings of sufficient evidence of
carcinogenicity in both humans and experimental animals.
NTP has classified respirable crystalline silica as a known
human carcinogen based on sufficient evidence of
carcinogenicity from studies in humans indicating a causal
relationship between occupational exposure to respirable
crystalline silica and increased lung cancer rates. NIOSH has
determined that respirable crystalline silica is a potential
occupational carcinogen.
IARC has determined that occupational exposure to Titanium
Dioxide is possibly carcinogenic to humans (Group 2B). IARC
concluded lung tumors were observed in rats following high
doseexposure by inhalation and in female rats exposed by
intra-tracheal instillation. Other studies have shown no tumors
in rats following inhalation exposure and no tumors in mice or
rats following oral exposure.