SDS

SAFETY DATA SHEET
Genetron® 410A
000000009881
Page 11 / 15
Version 2.7 Revision Date 04/18/2014 Print Date 04/14/2015
: Cell type: Chinese Hamster Ovary Cells
Result: negative
: Cell type: Human lymphocytes
Result: negative
Method: Mutagenicity (in vitro mammalian cytogenetic test)
: Test Method: Chromosome aberration test in vitro
Result: negative
Genotoxicity in vivo
Difluoromethane : Species: mouse
Cell type: Bone marrow
Method: Mutagenicity (micronucleus test)
Result: negative
Teratogenicity
Pentafluoroethane : Species: rabbit
Application Route: Inhalation exposure
NOAEL,Teratog: 50,000 ppm
NOAEL,Maternal: 50,000 ppm
Note: Did not show teratogenic effects in animal experiments.
Species: rat
Application Route: Inhalation exposure
NOAEL,Teratog: 50,000 ppm
NOAEL,Maternal: 50,000 ppm
Note: Did not show teratogenic effects in animal experiments.
Difluoromethane : Species: rat
Dose: NOEL - 50,000 ppm
Note: Did not show teratogenic effects in animal experiments.
Species: rabbit
Dose: NOEL - 50,000 ppm
Note: Did not show teratogenic effects in animal experiments.
Further information : Acute toxicity Vapours are heavier than air and can cause
suffocation by reducing oxygen available for breathing. Rapid
evapouration of the liquid may cause frostbite. May cause