Safety Data Sheet

Carcinogenicity
Risk of cancer cannot be excluded with prolonged exposure. In 2012 USEPA Integrated Risk
Information System (IRIS) reviewed a two species inhalation lifetime study on THF conducted by
NTP (1998). Male rats developed renal tumors and female mice developed liver tumors while
neither the female rats nor the male mice showed similar results. Because the carcinogenic
mechanisms could not be identified clearly in either species for either tumor, the EPA determined
that the male rat and female mouse findings are relevant to the assessment of carcinogenic
potential in humans. Therefore, the IRIS review concludes that these data in aggregate indicate
that there is "suggestive evidence of carcinogenic potential" following exposure to THF by all
routes of exposure. This product contains polyvinyl chloride (PVC) that is not a fabricated product,
and is therefore, defined and regulated as a toxic and hazardous substance under 29 C.F.R. §
1910.1017 due to the presumed presence of residual vinyl chloride monomer. The concentrations
of residual vinyl chloride calculated to be contained in this product are well below the threshold for
classification in accordance with 29 C.F.R. § 1910.1200.
IARC Monographs. Overall Evaluation of Carcinogenicity
Cyclohexanone (CAS 108-94-1) 3 Not classifiable as to carcinogenicity to humans.
Fumed Silica (CAS 112945-52-5) 3 Not classifiable as to carcinogenicity to humans.
Polyvinyl chloride (CAS 9002-86-2) 3 Not classifiable as to carcinogenicity to humans.
Tetrahydrofuran (CAS 109-99-9) 2B Possibly carcinogenic to humans.
NTP Report on Carcinogens
Not listed.
OSHA Specifically Regulated Substances (29 CFR 1910.1001-1053)
Polyvinyl chloride (CAS 9002-86-2) Cancer
This product is not expected to cause reproductive or developmental effects.
Reproductive toxicity
Specific target organ toxicity -
single exposure
May cause respiratory irritation. May cause drowsiness and dizziness.
Specific target organ toxicity -
repeated exposure
Not classified.
Aspiration hazard
May be fatal if swallowed and enters airways.
Chronic effects
Prolonged inhalation may be harmful. Frequent or prolonged contact may defat and dry the skin,
leading to discomfort and dermatitis.
12. Ecological information
The product is not classified as environmentally hazardous. However, this does not exclude the
possibility that large or frequent spills can have a harmful or damaging effect on the environment.
Ecotoxicity
Components Test ResultsSpecies
Acetone (CAS 67-64-1)
Aquatic
Acute
LC50Crustacea 8800 mg/l, 48 HoursDaphnia pulex
LC50Fish 7163 mg/l, 96 HoursPimephales promelas
Chronic
NOECCrustacea > 79 mg/l, 21 daysDaphnia magna
Cyclohexanone (CAS 108-94-1)
Aquatic
Acute
LC50Fish 527 mg/l, 96 HoursPimephales promelas
Methyl ethyl ketone (CAS 78-93-3)
Aquatic
Acute
EC50Crustacea 5091 mg/l, 48 HoursDaphnia magna
LC50Fish 3220 mg/l, 96 HoursPimephales promelas
Tetrahydrofuran (CAS 109-99-9)
Aquatic
Acute
LC50Crustacea 5930 mg/l, 24 HoursDaphnia magna
LC50Fish 2160 mg/l, 96 HoursPimephales promelas
Hercules PVC Medium Body Fast Set Cement SDS US
948998 Version #: 01 Revision date: - Issue date: 02-April-2019
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