SDS

SAFETY DATA SHEET
Freon™ 410A (R-410A) Refrigerant
Version
10.5
Revision Date:
10/10/2020
SDS Number:
1336443-00045
Date of last issue: 02/27/2020
Date of first issue: 02/27/2017
10 / 16
Method: OECD Test Guideline 471
Result: negative
Test Type: Chromosome aberration test in vitro
Method: OECD Test Guideline 473
Result: negative
Genotoxicity in vivo
:
Test Type: Mammalian erythrocyte micronucleus test (in vivo
cytogenetic assay)
Species: Mouse
Application Route: inhalation (gas)
Method: OECD Test Guideline 474
Result: negative
Germ cell mutagenicity -
Assessment
:
Weight of evidence does not support classification as a germ
cell mutagen.
Carcinogenicity
Not classified based on available information.
IARC
No ingredient of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
OSHA
No component of this product present at levels greater than or equal to 0.1% is
on OSHA’s list of regulated carcinogens.
NTP
No ingredient of this product present at levels greater than or equal to 0.1% is
identified as a known or anticipated carcinogen by NTP.
Reproductive toxicity
Not classified based on available information.
Components:
Pentafluoroethane:
Effects on fertility
:
Test Type: One-generation reproduction toxicity study
Species: Rat
Application Route: inhalation (vapor)
Result: negative
Remarks: Based on data from similar materials
Effects on fetal development
:
Test Type: Embryo-fetal development
Species: Rat
Application Route: inhalation (gas)
Method: OECD Test Guideline 414
Result: negative
Difluoromethane:
Effects on fertility
:
Species: Mouse
Application Route: Inhalation
Result: negative
Remarks: Based on data from similar materials
Effects on fetal development
:
Test Type: Combined repeated dose toxicity study with the