SDS
Attention should be paid to atopic diathesis, characterised by increased susceptibility to nasal inflammation, asthma and eczema.
Exogenous allergic alveolitis is induced essentially by allergen specific immune-complexes of the IgG type; cell-mediated reactions (T
lymphocytes) may be involved. Such allergy is of the delayed type with onset up to four hours following exposure.
The following information refers to contact allergens as a group and may not be specific to this product.
Contact allergies quickly manifest themselves as contact eczema, more rarely as urticaria or Quincke's oedema. The pathogenesis of
contact eczema involves a cell-mediated (T lymphocytes) immune reaction of the delayed type.
PlasticBonder™ Syringe Black -
Part A & SILICA AMORPHOUS
For silica amorphous:
Derived No Adverse Effects Level (NOAEL) in the range of 1000 mg/kg/d.
In humans, synthetic amorphous silica (SAS) is essentially non-toxic by mouth, skin or eyes, and by inhalation. Epidemiology studies show
little evidence of adverse health effects due to SAS. Repeated exposure (without personal protection) may cause mechanical irritation of
the eye and drying/cracking of the skin.
When experimental animals inhale synthetic amorphous silica (SAS) dust, it dissolves in the lung fluid and is rapidly eliminated.
PlasticBonder™ Syringe Black -
Part A & 4,4'-DIPHENYLMETHANE
DIISOCYANATE (MDI) & MDI,
PROPOXYLATED & MDI
HOMOPOLYMER
Isocyanate vapours are irritating to the airways and can cause their inflammation, with wheezing, gasping, severe distress, even loss of
consciousness and fluid in the lungs. Nervous system symptoms that may occur include headache, sleep disturbance, euphoria,
inco-ordination, anxiety, depression and paranoia.
4,4'-DIPHENYLMETHANE
DIISOCYANATE (MDI) & MDI
HOMOPOLYMER & MDI,
PROPYLENE GLYCOL,
TRIMETHYLOLPROPANE,TRIETHER
& SILICA AMORPHOUS
The substance is classified by IARC as Group 3:
NOT
classifiable as to its carcinogenicity to humans.
Evidence of carcinogenicity may be inadequate or limited in animal testing.
4,4'-DIPHENYLMETHANE
DIISOCYANATE (MDI) &
PROPYLENE CARBONATE
The material may produce moderate eye irritation leading to inflammation. Repeated or prolonged exposure to irritants may produce
conjunctivitis.
MDI, PROPOXYLATED & MDI,
PROPYLENE GLYCOL,
TRIMETHYLOLPROPANE,TRIETHER
No significant acute toxicological data identified in literature search.
Polyethers (such as ethoxylated surfactants and polyethylene glycols) are highly susceptible to being oxidized in the air. They then form
complex mixtures of oxidation products.
Animal testing reveals that whole the pure, non-oxidised surfactant is non-sensitizing, many of the oxidation products are sensitisers. The
oxidization products also cause irritation.
Acute Toxicity
Carcinogenicity
Skin Irritation/Corrosion
Reproductivity
Serious Eye Damage/Irritation
STOT - Single Exposure
Respiratory or Skin
sensitisation
STOT - Repeated Exposure
Mutagenicity
Aspiration Hazard
Legend:
– Data either not available or does not fill the criteria for classification
– Data available to make classification
SECTION 12 Ecological information
Toxicity
PlasticBonder™ Syringe
Black - Part A
Endpoint
Test Duration (hr)
Species
Value
Source
Not Available
Not Available
Not Available
Not Available
Not Available
4,4'-diphenylmethane
diisocyanate (MDI)
Endpoint
Test Duration (hr)
Species
Value
Source
BCF
672h
Fish
61-150
7
EC50
48h
Crustacea
>100mg/l
2
LC50
96h
Fish
95.24-134.37mg/l
Not Available
NOEC(ECx)
504h
Crustacea
>=10mg/l
2
MDI, propoxylated
Endpoint
Test Duration (hr)
Species
Value
Source
Not Available
Not Available
Not Available
Not Available
Not Available
MDI homopolymer
Endpoint
Test Duration (hr)
Species
Value
Source
NOEC(ECx)
504h
Crustacea
>=10mg/l
2
zeolites
Endpoint
Test Duration (hr)
Species
Value
Source
EC50
72h
Algae or other aquatic plants
>1000mg/l
2
EC50
48h
Crustacea
100-1800mg/l
1
EC50
96h
Algae or other aquatic plants
18mg/l
1
ErC50
72h
Algae or other aquatic plants
18mg/l
1
LC50
96h
Fish
1000mg/l
1
EC10(ECx)
96h
Algae or other aquatic plants
4.9mg/l
1
Version No:
11.16
Page
10
of
14
PlasticBonder™ Syringe Black - Part A
Issue Date:
12/07/2023
Print Date:
12/07/2023
Continued...