Owner manual

Chapter 4: Using Your Stoppering Tray Dryer
Product Service 1-800-522-7658
26
When all of the vials appear to be stoppered, move the Stoppering control to the
“LOWER” position. This opens the diaphragm to the vacuum pump, which
deflates the diaphragm. Opening the vacuum release control also deflates the
stoppering diaphragm. The Stoppering control should be left in the “LOWER”
position when not stoppering.
Vacuum Break/Backfilling
To open the chamber door, the vacuum must be released. To release the vacuum,
move the Vacuum Release control to the “OPEN” position and shut off the
vacuum pump using the switch on the base unit.
Air enters the vacuum chamber through the Back Fill port. When the sound of air
through the Back Fill port is no longer audible, the chamber door is ready to open.
To backfill the chamber with a gas, connect a cylinder of the desired gas to the
Back Fill port. The port will accept 1/8" tubing. The bottle must be equipped
with a regulator set to 15 psi maximum. The gas can be metered with the
Vacuum Release control and chamber pressure monitored with the freeze dry
system’s vacuum gauge. Allow the vacuum pump to run for a few minutes while
the gas enters to permit the back fill gas to surround the freeze dried sample.
When the vacuum pump is turned off, air will enter the system through the
vacuum break valve located between the vacuum pump and the collector
chamber.
Alarms
A number of unusual events may occur during a lyophilization procedure that can
adversely effect the operation of the Stoppering Tray Dryer. If an event occurs,
the alarm indicator will flash and the beeper will sound.
The beeper will automatically mute itself after one minute. The specific alarm
can be identified observing the display. The following “out of specification”
conditions will initiate an alarm:
System Temperature Variations
Once the system temperature has stabilized for 20 minutes, if the manual set point
temperature or automatic hold temperature varies more than ±2°C as measured by
the system temperature sensor, the Red Alarm indicator and the word “TMP” on
the display will flash. Pressing Run/Stop or turning off the power switch cancels
the flashing warning.
Vacuum
Once the system vacuum is low and stabilized at a point where it changes less
than 0.020 mBar in 5 minutes, if the vacuum changes more than 0.500 mBar, the
Red Alarm indicator and the word “VAC” on the display will flash. Pressing
Run/Stop or turning off the power switch cancels the flashing warning.