SDS

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Safety data sheet
according to 1907/2006/EC, Article 31
Printing date 19.11.2019 Revision: 19.11.2019Version number 1
Trade name: HFC-32
(Contd. of page 4)
49.4.19.1
Other information (about experimental toxicology):
Chromosomal Aberration Study in vitro- Negative
Mouse Micronucleus Assay in Vivo - Negative
Repeated dose toxicity
NOAEC (inhalation): 105000 mg/m³ (rat) (OECD 413)
CMR effects
Mutagenicity:
Ames test: negative (OECD 471)
In vitro mammalian chromosome aberration test: negative (OECD 473)
Mammalian erythrocyte micronucleus test: negative (OECD 474)
Toxicity for reproduction:
NOAEC (inhalation): 208000 mg/m³ (mouse) (OECD 478; read across)
Developmental toxicity:
NOAEC (inhalation): 105000 mg/m³ (rat)
Germ cell mutagenicity
Not applicable
Carcinogenicity
Based on available data, the classification criteria are not met.
Reproductive toxicity
Based on available data, the classification criteria are not met.
STOT-single exposure
Based on available data, the classification criteria are not met.
STOT-repeated exposure
Based on available data, the classification criteria are not met.
Aspiration hazard
Based on available data, the classification criteria are not met.
SECTION 12: Ecological information
12.1 Toxicity
Aquatic toxicity:
EC50/96 h 142 mg/l (algae) (QSAR)
LC50/48 h 652 mg/l (daphnia) (QSAR)
LC50/96 h 1507 mg/l (fish) (QSAR)
12.2 Persistence and degradability:
Not easily biodegradable
5% after 28 days (OECD 301 D)
Behaviour in environmental systems
Components:
Half-life in air: 1237 days
12.3 Bioaccumulative potential:
Due to the distribution coefficient n-octanol/water an accumulation in organisms is not expected.
12.4 Mobility in soil:
No further relevant information available.
Other information
Koc = 1.49 - 21-73 (QSAR)
log Koc = 0.17 - 1.34 (QSAR)
Additional ecological information:
General notes:
Ozone depletion potential(ODP) : 0
Global warming potential(GWP) : 675 / IPCC Fourth Assessment Report (AR4)
12.5 Results of PBT and vPvB assessment
PBT:
Not applicable.
vPvB:
Not applicable.
12.6 Other adverse effects:
No further relevant information available.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Recommendation:
Must be specially treated adhering to official regulations.
Incineration in an adequate incinerator is recommended.
Uncleaned packaging
Recommendation:
Disposal must be made according to official regulations.
(Contd. on page 6)