Safety data sheet

Safety data sheet according to Regulation (EC) No 1907/2006, Annex II
Revision date / version: 21.08.2015 / 0011
Replacing version dated / version: 10.06.2015 / 0010
Valid from: 21.08.2015
PDF print date: 27.08.2015
Liquimate 7700 mini Rapid 25 mL
Art.: 6126 (B)
Specific target organ toxicity -
repeated exposure (STOT-RE):
NOAEL 0,2 Rat OECD 453 (Combined
Chronic
Toxicity/Carcinogenicity
Studies)
Aerosol, Analogous
conclusion
Specific target organ toxicity -
repeated exposure (STOT-RE):
LOAEL 1 Rat OECD 453 (Combined
Chronic
Toxicity/Carcinogenicity
Studies)
Aerosol, Analogous
conclusion
Symptoms: respiratory distress,
coughing, mucous
membrane irritation
Specific target organ toxicity -
single exposure (STOT-SE),
inhalative:
Irritation of the respiratory
tract
Specific target organ toxicity -
repeated exposure (STOT-RE),
inhalat.:
Target organ(s):
respiratory system
o-(p-isocyanatobenzyl)phenylisocyanate
Toxicity / effect Endpoin
t
Value Unit Organism Test method Notes
Acute toxicity, by oral route: LD50 >2000 mg/kg Rat Regulation (EC)
440/2008 B.1 (ACUTE
ORAL TOXICITY)
Analogous conclusion
Acute toxicity, by dermal route: LD50 >9400 mg/kg Rabbit OECD 402 (Acute
Dermal Toxicity)
Analogous conclusion
Skin corrosion/irritation: Rabbit OECD 404 (Acute
Dermal
Irritation/Corrosion)
Irritant, Analogous
conclusion
Respiratory or skin sensitisation: Mouse OECD 429 (Skin
Sensitisation - Local
Lymph Node Assay)
Analogous conclusion,
Sensitising (inhalation
and skin contact)
Germ cell mutagenicity: Salmonella
typhimurium
OECD 471 (Bacterial
Reverse Mutation Test)
Negative
Carcinogenicity: Rat OECD 453 (Combined
Chronic
Toxicity/Carcinogenicity
Studies)
Aerosol, Analogous
conclusion, Limited
evidence of a
carcinogenic effect.
Reproductive toxicity
(Developmental toxicity):
NOAEL 0,004 mg/l Rat OECD 414 (Prenatal
Developmental
Toxicity Study)
Aerosol, Negative,
Analogous conclusion
Specific target organ toxicity -
repeated exposure (STOT-RE):
NOAEL 0,2 Rat OECD 453 (Combined
Chronic
Toxicity/Carcinogenicity
Studies)
Aerosol, Analogous
conclusion
Specific target organ toxicity -
repeated exposure (STOT-RE):
LOAEL 1 Rat OECD 453 (Combined
Chronic
Toxicity/Carcinogenicity
Studies)
Aerosol, Analogous
conclusion
Symptoms: asthmatic symptoms,
mucous membrane
irritation
Specific target organ toxicity -
single exposure (STOT-SE),
inhalative:
May cause respiratory
irritation.
Specific target organ toxicity -
repeated exposure (STOT-RE),
inhalat.:
Target organ(s):
respiratory system
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane
Toxicity / effect Endpoin
t
Value Unit Organism Test method Notes
Acute toxicity, by oral route: LD50 8025 mg/kg Rat OECD 401 (Acute Oral
Toxicity)
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