Safety data sheet

SDS No.: 153465 V007.0
LOCTITE 272
Page 13 of 19
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
negative
in vitro mammalian
cell micronucleus
test
with and without
OECD Guideline 487 (In vitro
Mammalian Cell
Micronucleus Test)
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
positive
in vitro mammalian
cell micronucleus
test
with and without
OECD Guideline 487 (In vitro
Mammalian Cell
Micronucleus Test)
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
N,N-(m-
phenylene)dimaleimide
3006-93-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
N,N-(m-
phenylene)dimaleimide
3006-93-7
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
N,N-(m-
phenylene)dimaleimide
3006-93-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Hydroxypropyl
methacrylate
27813-02-1
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Hydroxypropyl
methacrylate
27813-02-1
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Cumene hydroperoxide
80-15-9
positive
bacterial reverse
mutation assay (e.g
Ames test)
without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Maleic acid
110-16-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
no data
Ames Test
Maleic acid
110-16-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Carcinogenicity
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous components
CAS-No.
Result
Route of
application
Exposure
time /
Frequency
of treatment
Species
Sex
Method
Hydroxypropyl
methacrylate
27813-02-1
not carcinogenic
inhalation
2 years (102
weeks)
6 hours/day,
5 days/week
rat
male
OECD Guideline 451
(Carcinogenicity
Studies)
Maleic acid
110-16-7
not carcinogenic
oral: feed
2 y
daily
rat
male/female
OECD Guideline 451
(Carcinogenicity
Studies)