Safety data sheet

SDS No.: 232327 V006.0
LOCTITE SF 7061 known as Loctite 7061 400ML M/L
Page 11 of 17
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Acetone
67-64-1
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Acetone
67-64-1
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Acetone
67-64-1
negative
mammalian cell
gene mutation assay
without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Ethanol
64-17-5
negative
bacterial reverse
mutation assay (e.g
Ames test)
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Ethanol
64-17-5
negative
in vitro mammalian
chromosome
aberration test
without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Ethanol
64-17-5
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Propan-2-ol
67-63-0
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Propan-2-ol
67-63-0
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Acetone
67-64-1
negative
oral: drinking water
mouse
not specified
Ethanol
64-17-5
negative
OECD Guideline 475
(Mammalian Bone Marrow
Chromosome Aberration Test)
Propan-2-ol
67-63-0
negative
intraperitoneal
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
Carcinogenicity
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous components
CAS-No.
Result
Route of
application
Exposure
time /
Frequency
of treatment
Species
Sex
Method
Acetone
67-64-1
not carcinogenic
dermal
424 d
3 times per
week
mouse
female
not specified
Ethanol
64-17-5
oral:
unspecified
rat
not specified
Ethanol
64-17-5
dermal
mouse
female
not specified
Ethanol
64-17-5
inhalation
mouse
male
not specified
Propan-2-ol
67-63-0
inhalation:
vapour
104 w
6 h/d, 5 d/w
rat
male/female
OECD Guideline 451
(Carcinogenicity
Studies)