SDS

9
CONTINUED: SECTION 11. TOXICOLOGICAL INFORMATION
- Graphite : Rat LD50 ＞ 2,000 mg/kg (female)(OECD Guideline 401)
- Fe : Rat LD50 = 98,600 mg/kg (Reduced iron, OECD TG 401)
- Copper : Rat LD50 ＞ 2,500 mg/kg (Cupric oxide; read across)(OECD TG 423, GLP)
- Aluminum : Rat LD50 ＞ 15,900 mg/kg (OECD TG 401)(Fumed alumina; read across)
- Lithium hexafluorophosphate(1-) : Rat LD50 = 50 ~ 300 mg/kg (Female)(OECD Guideline 423, GLP)
- 4-fluoro-1,3-dioxolan-2-one : Rat LD50 = 500 mg/kg (male)(OECD Guideline 423)
- Dimethyl carbonate : Rat LD50 ＞ 5,000 mg/kg (male/female) (OECD Guideline 401)
- Polyethylene : Rat LD50 ＞ 2,000 mg/kg
- Diiron trioxide : Rat LD50 ＞ 5,000 mg/kg (male/female)(EU Method B.1)
- Boehmite (Al(OH)O) : Rat LD50 ＞ 2,000 mg/kg (OECD Guideline 423, GLP)
- Carbon black : Rat LD50 ＞ 8,000 mg/kg (OECD TG 401)
- Nickel; Raney nickel : Rat LD50 ＞ 9,000 mg/kg (male/female) (OECD Guideline 401, GLP)
- 1-Methyl-2-pyrrolidinone : Rat LD50 = 4,150 mg/kg (male/female)(OECD Guideline 401)
- Chromium : Rat LD50 ＞ 5,000 mg/kg (Read across; chromium(III) oxide)(OECD TG 420, GLP)
- Lithium carbonate;Lithane : Rat LD50 = 525 mg/kg
- Ethylbenzene : Rat LD50 = 3,500 mg/kg (male or female)
Dermal : ATEmix = 1,651,224 mg/kg bw
- Copper : Rat LD50 ＞ 2,000 mg/kg (OECD TG 402, GLP)
-4-fluoro-1,3-dioxolan-2-one : Rat LD50 ＞ 2,000 mg/kg (male/female) (OECD Guideline 402)
-Dimethyl carbonate : Rabbit LD50 ＞ 2,000 mg/kg (male/female)
- 1-Methyl-2-pyrrolidinone : Rat LD50 ＞ 5,000 mg/kg (male/female) (OECD Guideline 402)
- Lithium carbonate;Lithane : Rabbit LD50 ＞ 3,000 mg/kg (male/female) (OECD Guideline 402)
- Ethylbenzene : Rabbit LD50 = 15,432 mg/kg
Inhalation : ATEmix = 226.04 mg/L
- Graphite : Rat LD50 ＞ 2 mg/L/4hr (male/female) (OECD Guideline 403)
- Fe : Rat LC50 ＞ 100 mg/m³/6hr
- Aluminum : Rat LC50 ＞ 0.888 mg/L/4hr (analytical) (OECD TG 403)
- Dimethyl carbonate : Rat LD50 ＞ 5.36 mg/L/4hr (male/female) (OECD Guideline 403)
- Diiron trioxide : Rat LC50 = 5.05 mg/L/4hr (male/female) (OECD Guideline 403, GLP)
- Boehmite (Al(OH)O) : Rat LD50 ＞ ~ 0.888 mg/kg/4hr (OECD Guideline 403, GLP)
- Carbon black : Rat LC50 ＞ 0.005 mg/L/4hr
- 1-Methyl-2-pyrrolidinone : Rat LC50 ＞ 5.1 mg/L/4hr (male/female) (OECD Guideline 403)
- Chromium : Rat LD50 ＞ 5.41 mg/L/4hr (Read across; chromium(III) oxide)(OECD TG 403, GLP)
- Lithium carbonate;Lithane : Rat LC50 ＞ 2 mg/L/4hr (male/female) (OECD Guideline 403)
- Ethylbenzene : Rat LC50 = 17.8 mg/L/4hr
Skin corrosion/ irritation :
- Graphite : In the skin irritation test using rabbits, the test material was not irritating. (OECD Guideline 404, GLP)
- Fe : In test on skin irritation with rabbits, skin irritations were not observed.(Read across; Fe3O4)(OECD TG 404, GLP)
- Copper : In test on skin irritation with rabbits, skin irritations were not observed. (OECD TG 404, GLP)
- Aluminum : Aluminium oxide caused slight erythema in 2/12 rabbits. The observed effects do not lead to a classification.
Aluminium oxide is, therefore, not considered to be a primary skin irritant.(OECD TG 404)(Read across; aluminum oxide)
- Lithium hexafluorophosphate (1-) : In the skin irritation test using human, the test material was corrosive. (EU Method B.40, GLP)
- 4-fluoro-1,3-dioxolan-2-one : In the skin irritation test using human skin model, the test material was non-corrosive. (OECD
Guideline 431, GLP)
- Dimethyl carbonate : In the skin irritation test using rabbits, the test material was not irritating. (OECD Guideline 404)
- Polyethylene : No irritation was observed at the other two treated sites and no corrosive effects were noted during the study using
rabbits. The primary irritation index was calculated as 0.2 and polyethylene was classified as a mild irritant.
- Diiron trioxide : In the skin irritation test using rabbits, the test material was not irritating. (OECD Guideline 404, GLP)
- Boehmite (Al(OH)O) : In the skin irritation test using rabbits, skin irritations were not observed.(OECD Guideline 404, GLP)
- Carbon black : In test on skin irritation with rabbits, skin irritations were not observed. (OECD TG 404)
- Nickel; Raney nickel : Industrial nickel dust causes nickel dermatitis.