Instruction Manual

ManualsBrandsMartin Christ ManualsEquipmentAlpha 1-2 LDplus

Operating Manual

Freeze-dryer

Alpha 1-2 LDplus

from serial no. 101521

Translation of the original operating manual

Version 11/2006

Rev. 2.0 of 02/12/2014

Alpha 1-2 LDplus; ;

Summary of content (96 pages)

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Operating Manual Freeze-dryer Alpha 1-2 LDplus from serial no. 101521 Translation of the original operating manual sb Version 11/2006 Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 2 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus In case of inquiries, please state the following numbers: Order number Serial number © Copyright by Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Söse 50 37520 Osterode am Harz Germany Tel.: +49 (0) 5522 / 5007-0 Fax: +49 (0) 5522 / 5007-12 Web: www.martinchrist.de E-mail: info@martinchrist.de Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus Table of contents 1 General information ............................................................................................................. 9 1.1 Importance of the operating manual.................................................................................. 9 1.2 Intended use ..................................................................................................................... 9 1.3 Warranty and liability.....................................
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Freeze-dryer Alpha 1-2 LDplus Table of contents 4 Storage and transport ....................................................................................................... 29 4.1 Dimensions and weight ................................................................................................... 29 4.2 Storage conditions .......................................................................................................... 29 4.3 Notes on transport .........................................
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Freeze-dryer Alpha 1-2 LDplus Table of contents 8 Maintenance and service................................................................................................... 56 8.1 Maintenance ................................................................................................................... 56 8.1.1 Freeze-dryer .............................................................................................................. 56 8.1.1.1 Ice condenser chamber.....................................
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Freeze-dryer Alpha 1-2 LDplus 1 General information Pos: 1 /2 00 C hrist/ 360 GT -BA Lab or-Pilot (STANDARDM ODULE)/ 010 Allg emei ne I nfor mati one n/01 0 Allge mein e In for matio nen == == === == == === == == == === == == === == @ 24 \mo d_1 404 983 207 982_ 68. docx @ 18 2921 @ 1 @ 1 1 General information Pos: 2 /2 00 C hrist/ 360 GT -BA Lab or-Pilot (STANDARDM ODULE)/ 010 Allg emei ne I nfor mati one n/01 0-0 010 Stelle nwert de r Betri ebsa nleitu ng @ 25\ mod _14 049 832 092 48_6 8.
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Freeze-dryer Alpha 1-2 LDplus 1 General information Pos: 6 /2 00 C hrist/ 360 GT -BA Lab or-Pilot (STANDARDM ODULE)/ 010 Allg emei ne I nfor mati one n/01 0-0 030 Gew ährl eistun g u nd Ha ftun g @ 2 5\m od_ 140 498 321 137 7_68 .docx @ 1 829 63 @ 2 @ 1 1.3 Warranty and liability The warranty and liability are subject to our "General Terms and Conditions" that were distributed to the operator upon the conclusion of the contract.
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Freeze-dryer Alpha 1-2 LDplus 1 General information Pos: 14 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Alpha 1- 2 LDpl us/0 10 Allge mein e Inf or matio nen/ 010 -00 70 Lief eru mfa ng Alph a 1 -2 LD plus @ 31\ mod _14 080 840 313 28_6 8.d ocx @ 209 283 @ 2 @ 1 1.7 Scope of supply The scope of supply comprises: • 1 tube of high-vacuum grease • 1 drain hose 0.
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Freeze-dryer Alpha 1-2 LDplus 2 Layout and mode of operation Pos: 17 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /02 0 Aufb au u nd Wirk ungs weise/ 020 Aufb au u nd Wir kung sweise == === == == === == == === == == === = @ 25\ mod _14 049 832 3599 4_6 8.
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Freeze-dryer Alpha 1-2 LDplus 2 Layout and mode of operation 5 6 User interface (see chapter 6.5.1 - "User interface") Mains power switch Fig. 3: Front and right side of the freeze-dryer 7 8 9 Name plate (see chapter 2.1.
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Freeze-dryer Alpha 1-2 LDplus 2 Layout and mode of operation Pos: 21 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Alpha 1- 2 LDpl us/0 20 Auf bau und Wirkun gsweis e/02 0-0 010 -00 20 Typ enschil d Alpha 1- 2 LDpl us @ 31\ mod _140 808 404 715 5_6 8.doc x @ 2 093 12 @ 3 @ 1 2.1.
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Freeze-dryer Alpha 1-2 LDplus 2 Layout and mode of operation Pos: 23 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /02 0 Aufb au u nd Wirk ungs weise/ 020 -00 20 Wi rkun gsweise -- --- --- -- --- -- --- -- --- - @ 25\m od_ 140 498 325 385 0_6 8.docx @ 1 830 47 @ 2 @ 1 2.2 Mode of operation Pos: 24 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /02 0 Aufb au u nd Wirk ungs weise/ 020 -00 20- 001 0 G efrie rtr ocknu ng allgem ein @ 25\ mod _14 049 832 548 15_ 68.
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Freeze-dryer Alpha 1-2 LDplus 2 Layout and mode of operation Melting point pressure curve Pressure (mbar) SOLID A Melting B Sublimation 0.37 mbar V Su apo bl ur im p at res io s n ur pr e es cu su rv re e f cu or rv ice e = 6.11 mbar LIQUID ou Vap r ssu pre e urv re c Evaporation Triple point GASEOUS -30°C Temperature (°C) Fig.
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Freeze-dryer Alpha 1-2 LDplus 2 Layout and mode of operation Pressure (mbar) 1 bar LIQUID Melting point pressure curve 1 SOLID cur ve Triple point Va p su ou bl r p im re at ss io ur n e pr cu es rv su e re for cu ic rv e = e 2 ou Vap ur e ess r pr GASEOUS 20°C Temperature (°C) Fig. 7: Freeze-drying phases Please find further information about basic principles, optimum procedures and applications in the brochure "Smart freeze-drying", which can be downloaded at www.martinchrist.
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Freeze-dryer Alpha 1-2 LDplus 2 Layout and mode of operation Pos: 26 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /02 0 Aufb au u nd Wirk ungs weise/ 020 -00 20- 002 0 Abla uf ei nes G efrie rtr ockn ungs proz esses @ 25 \mo d_1 404 983 2559 39_ 68. docx @ 18 3075 @ 3 @ 1 2.2.
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Freeze-dryer Alpha 1-2 LDplus 2 Layout and mode of operation Fig. 8: Shell freezing Fig. 9: Cooling bath with spin freezing device NOTE Fig. 10: Spin freezing If the product that is to be dried contains solvents or high salt concentrations, it may start to thaw during the drying process, which is indicated by clearly visible foaming. In order to prevent this, the product must be frozen as deeply as possible, e.g. with the aid of liquid nitrogen, prior to putting it into the unit.
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Freeze-dryer Alpha 1-2 LDplus 2 Layout and mode of operation The end of the main drying phase is reached, when the product temperature and the shelf temperature are nearly identical. The temperature difference between the shelf and the product should be approximately 3 K to 5 K. Pos: 34 / 010 Unive rsalm odul e/Le erzeil e @ 0\mo d_1 202 116 244 500 _0.
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Freeze-dryer Alpha 1-2 LDplus 3 Safety Pos: 42 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 Siche rheit == === == == === == == == === == == === == == === @ 2 5\m od_ 1404 983 296 098 _68. docx @ 18 320 1 @ 1 @ 1 3 Safety Pos: 43 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 10 B eschilde ru ng d es Ge räts @ 2 5\mo d_1 404 983 297 040 _68. docx @ 18 321 5 @ 2 @ 1 3.
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Freeze-dryer Alpha 1-2 LDplus 3 Safety Pos: 45 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 20 Sy mbol - un d Hinw eiserkl äru nge n @ 2 5\m od_ 140 498 3298 133 _68 .docx @ 1 8322 9 @ 2 @ 1 3.2 Explanation of the symbols and notes This operating manual uses the following names and symbols to indicate hazards: This symbol stands for a direct hazard to the life and health of persons.
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Freeze-dryer Alpha 1-2 LDplus 3 Safety Pos: 47 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 30 V era ntwor tun g des Betr eiber s @ 2 5\m od_ 140 498 3299 227 _68 .docx @ 1 8324 3 @ 2 @ 1 3.3 Responsibility of the operator The operator is responsible to authorise only qualified personnel to work on the freeze-dryer (see chapter 3.4 - "Operating personnel").
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Freeze-dryer Alpha 1-2 LDplus 3 Safety Pos: 53 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 60 Sic her heitshi nweise ++ +++ ++ ++ +++ ++ ++ +++ ++ ++ ++ +++ + @ 25\ mod _14 0498 330 236 1_6 8.do cx @ 1 832 85 @ 2 @ 1 3.6 Safety instructions The following instructions must be observed prior to every drying process: • • WARNING • • • • • Ensure that the freeze-dryer was set up and connected properly (see chapter 5 - "Set-up and connection").
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Freeze-dryer Alpha 1-2 LDplus 3 Safety Pos: 58 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 60- 002 0 Mech anisch e Siche rheit @ 25 \mo d_1 404 983 304 593 _68. docx @ 18 331 3 @ 3 @ 1 3.6.2 Mechanical safety In order to ensure the safe operation of the freeze-dryer, please comply with the following points: • • • WARNING • • • • • • • Do not use the freeze-dryer if it was installed incorrectly. Do not use the freeze-dryer without panels.
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Freeze-dryer Alpha 1-2 LDplus 3 Safety Pos: 63 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 60- 004 0 The rmisc he Siche rhei t @ 2 5\m od_ 140 498 3306 816 _68 .docx @ 18 334 1 @ 3 @ 1 3.6.4 Thermal safety During the operation of the freeze-dryer, the ice condenser can reach surface temperatures of –85°C depending on the power. • Wear suitable protective gloves when installing or removing accessories.
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Freeze-dryer Alpha 1-2 LDplus 3 Safety Pos: 68 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 70 Sic her heitsei nricht ung en- -- --- -- --- --- -- --- -- --- -- --- --- -- --- -- --- --- -- --- -- -- @ 25\ mod _14 049 833 091 10_6 8.d ocx @ 183 369 @ 2 @ 1 3.7 Safety devices Pos: 69 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 70- 001 0 Syst emko ntr olle LD plus @ 31\ mod _14 085 1550 885 6_6 8.do cx @ 2 097 72 @ 3 @ 1 3.
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Freeze-dryer Alpha 1-2 LDplus 3 Safety Pos: 76 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 90 R estrisik en @ 25\ mod _14 049 833 155 77_ 68.d ocx @ 183 453 @ 2 @ 1 3.9 Remaining hazards All CHRIST freeze-dryers were built state-of-the-art and according to the accepted safety rules.
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Freeze-dryer Alpha 1-2 LDplus 4 Storage and transport Pos: 79 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /04 0 La ger ung und Tr ans port /040 L age run g un d T rans por t= === == == === == == === == == === == @ 2 5\mo d_1 404 983 713 664 _68.
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Freeze-dryer Alpha 1-2 LDplus 4 Storage and transport Pos: 85 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Alpha 1- 2 LDpl us/0 40 L age run g un d T ran spo rt/0 40- 0030 4.3 Tra nspo rthinw eise Alp ha 1 -2 LD plus @ 31\ mo d_1 4080 840 605 47_ 68.d ocx @ 209 341 @ 2 @ 1 Notes on transport • • • • Use suitable packaging for the transport, and if at all possible, the original packaging. Install all transport safety devices (see chapter 4.5 - "Transport safety device").
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Freeze-dryer Alpha 1-2 LDplus 4 Storage and transport Pos: 87 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Alpha 1- 2 LDpl us/0 40 L age run g un d T ran spo rt/0 40- 0040 Ver pack ung Alp ha 1 -2 LDplus @ 31 \mo d_1 408 084 061 156 _68. docx @ 20 935 5 @ 2 @ 1 4.4 Packaging The freeze-dryer is packaged in a cardboard box or in a wooden crate, depending on the scope of supply. • After opening the packaging, take out the box containing the accessories. • Remove the packaging material.
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Freeze-dryer Alpha 1-2 LDplus 5 Set-up and connection Pos: 92 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /05 0 Aufstell ung und Anschlus s/05 0 Aufs tellun g u nd Ansc hluss= == == === == == === == == == === == @ 25 \mo d_1 404 983 7372 44_ 68. docx @ 18 3495 @ 1 @ 1 5 Set-up and connection Pos: 93 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /05 0 Aufstell ung und Anschlus s/05 0-0 010 Aufst ellort (Alpha -Delt a) @ 25\ mod _14 049 837 381 97_ 68.d ocx @ 183 509 @ 2 @ 1 5.
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Freeze-dryer Alpha 1-2 LDplus 5 Set-up and connection Pos: 100 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Alph a 1 -2 LD plus/ 050 Au fstellu ng u nd Ansc hluss/ 050 -00 30 B elüftu ngs - un d M edien abla ufve ntil Alpha 1- 2 LDpl us @ 31\m od_ 140 808 408 064 5_68 .docx @ 2 094 12 @ 2 @ 1 5.3 Aeration and media drain valve The aeration and media drain valve is located on the left side of the unit. After the end of a freeze-drying process, the unit will be aerated via the aeration valve.
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Freeze-dryer Alpha 1-2 LDplus 5 Set-up and connection It is absolutely essential to comply with the manufacturer’s instructions in the separate operating manual of the vacuum sensor! NOTE Thyracont VSP62/63 MKS 722B Pfeiffer TPR 280/281 Fig. 14: Installed vacuum sensors of different manufacturers The vacuum sensor comes supplied in a calibrated state. NOTE After the freeze-dryer has been switched on, the vacuum sensor needs several minutes until it is ready for operation.
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Freeze-dryer Alpha 1-2 LDplus 5 Set-up and connection Pos: 104 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Alph a 1 -2 LD plus/ 050 Au fstellu ng u nd Ansc hluss/ 050 -00 60 V akuu mpu mpe Alpha 1-2 LDpl us @ 3 1\m od_ 140 808 408 1959 _68 .docx @ 2 094 54 @ 2 @ 1 5.4.6 Vakuum pum pe 5.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Pos: 109 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ 060 B etrie b= === == == === == == === == == === == == == === == == == @ 25\ mod _14 049 837 597 58_6 8.d ocx @ 183 578 @ 1 @ 1 6 Operation Pos: 110 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ 060 -00 10 E rste I nbe trie bnah me ++ +++ ++ ++ +++ ++ ++ +++ ++ ++ ++ + @ 2 5\m od_ 140 4983 760 674 _68. docx @ 18 359 2 @ 2 @ 1 6.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Pos: 118 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LDplus/ 060 -00 50 LDplu s Anlag enst eue rung -- --- -- --- -- --- --- -- --- -- --- --- -- --- -- --- -- -- @ 31\ mod _14 083 525 0124 6_6 8.d ocx @ 209 535 @ 2 @ 1 6.5 LDplus control system The control system LDplus ("Lyo Display plus") was specifically developed for the control of freeze-drying processes. The clear user interface enables the intuitive operation of the unit.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Display (5) The main window of the display is divided into the value windows, an area indicating the current function of the function keys, and a status line. The main window displays all of the relevant process data, such as set and actual values, menus, and process information (see the illustration). 6 7 8 Value window Current function of the function keys Status line Fig.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Status line (8) The status line at the bottom of the screen indicates the current operating state, active phase, and any pending information. The status line is visible at all times. 13 Symbol of the operating state 14 Active phase 15 Symbol of pending information Fig. 21: Status line Operating state (13) The freeze-dryer is in the standby mode. All of the various units are switched off. The freeze-dryer is in the run mode. The unit performs a continuous run.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Pos: 122 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LDplus/ 060 -00 50- 002 0 Mod us @ 31\ mod_ 140 835 250 197 8_6 8.docx @ 2 095 63 @ 3 @ 1 6.5.2 Mode The mode can be called up with the left function key if a value window is active. The individual phases can be selected as follows: • Press the left function key "mode". The menu "Start with phase..." will be displayed (see the illustration).
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Warm-up vacuum pump Prior to a freeze-drying process, the vacuum pump usually needs to warm up in order to reach its operating temperature. For this purpose, the warm-up phase can be started. The desired duration can be preselected (see chapter 6.5.3.4 - "Options"). The following processes take place during the warm-up phase. • The ice condenser is cooled. • The vacuum pump is activated while the pressure control valve is closed.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Pos: 124 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LDplus/ 060 -00 50- 003 0 H aupt men ü @ 31\ mod_ 140 835 250 250 6_6 8.doc x @ 2 095 78 @ 3 @ 1 6.5.3 Main menu The main menu can be selected from the main window by way of the right function key "menu". It includes the following submenus: • Change set values (see chapter 6.5.3.1 - "Changing set values") • Special functions (see chapter 6.5.3.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Set values for the "freezing" phase Timer The timer is used to define the duration of the phase. Settings between one minute and 200 hours are possible. If, when starting at 00:00 h:m, the "down" key is pressed, the symbol will appear. It indicates that the timer is deactivated and that the freeze-dryer is in the continuous mode. After the preselected time has elapsed, the system enquires as to whether the next phase is to be started.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Pos: 128 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LDplus/ 060 -00 50- 003 0-0 020 Son derf unkti one n @ 3 1\m od_ 140 8352 503 612 _68. docx @ 20 962 0 @ 4 @ 1 6.5.3.2 Special functions The freeze-dryer is equipped with one or several optional accessories. The components can be controlled by way of this function. • Select the "Special functions" function in the main menu. • Select the option by way of the up/down keys.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Option: Electrical lifting hoist The freeze-dryer can be retrofitted with an electrical lifting hoist that facilitates the attachment and removal of drying chambers. The freeze-dryer must be in the standby mode and completely aerated. The drying chamber cannot be moved in the "Main drying" and "Final drying" phases. NOTE • • Select the function "Lifting hoist" under "Special functions" in the main menu (see above).
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Status of the information All of the information that is displayed receives a certain status: Information present, not acknowledged Information present, acknowledged Cause of the message no longer present, information not acknowledged The sound signal is issued until all of the information has been acknowledged.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Fig. 37: Menu for selecting a language Settings This menu can be used to adapt the operation and process control of the freeze-dryer's control system to your specific requirements. • Select the desired menu. • Change the value by way of the up/down keys. • Confirm the entry with the right function key "ok". Fig. 38: "Settings" menu Warm-up vacuum pump This item is used to adjust the duration of the warm-up phase. Values between 5 and 60 minutes are possible.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Service menu Fig. 39: Service menu LDplus configuration Here, the following accessory components (options) can be configured: • Vacuum sensor • Vacuum control system • • Installed options must be activated with "yes". Options that are not installed must be deactivated with "no". NOTE Load default settings This menu item is used to reset all of the set values and parameters to the delivery state of the freeze-dryer.
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Freeze-dryer Alpha 1-2 LDplus 6 Operation Pos: 136 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ 060 -00 70 A usschalt en (nu r Netzs chalt er) ++ ++ ++ +++ ++ ++ +++ ++ ++ +++ ++ ++ @ 25 \mo d_1 404 983 7666 90_ 68. docx @ 18 3677 @ 2 @ 1 6.6 Switching the freeze-dryer OFF The freeze-dryer must be in the standby status. • Switch the freeze-dryer off by pressing the mains power switch. Pos: 137 /01 0 Univ ersal mod ule/Absc hnittsw echsel @ 0\ mod _12 021 245 140 62_ 0.
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Freeze-dryer Alpha 1-2 LDplus 7 Malfunctions and error correction Pos: 139 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 70 Stö run gen und Fe hlers uche /07 0 Stö run gen und Fe hlers uche == == === == == === == == === == == == @ 25\ mo d_14 049 840 560 39_ 68.d ocx @ 184 111 @ 1 @ 1 7 Malfunctions and error correction Malfunctions are displayed in the dialog box "Process & equipment messages" (see chapter 6.5.3.3 - "Process and equipment information").
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Freeze-dryer Alpha 1-2 LDplus 7 Malfunctions and error correction Fig. 41: Small flange and centring ring Fig. 42: Small flange with centring ring and small flange Fig. 43: Attaching the clamping ring Fig. 44: Tightened clamping ring Pos: 147 /01 0 Univ ersal mod ule/L eerz eile @ 0\m od_ 120 211 624 450 0_0.
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Freeze-dryer Alpha 1-2 LDplus 7 Malfunctions and error correction 7.1.2.3 Pressure control valve A malfunction of the pressure control valve may have several causes. The inspection of the valve must be carried out by qualified specialist personnel (see chapter 7.3 - "Service contact"). NOTE Pos: 151 /01 0 Univ ersal mod ule/Seit enwec hsel @ 0\m od_ 120 211 624 4312 _0.
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Freeze-dryer Alpha 1-2 LDplus 7 Malfunctions and error correction 7.1.3 Insufficient ice condenser temperature Ensure sufficient ventilation. Do not place any paper, cloth, or similar material behind or under the unit, since otherwise the air circulation will be impaired. CAUTION The refrigeration unit is equipped with a protective device against overpressure in the refrigeration system and with a thermal motor protection switch.
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Freeze-dryer Alpha 1-2 LDplus 7 Malfunctions and error correction Pos: 158 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 70 Stö run gen und Fe hlers uche /07 0-0 020 Proz ess un d Anla gen meld ung en LD plus @ 31\ mod _14 084 388 381 99_6 8.d ocx @ 209 732 @ 2 @ 1 7.2 Process and equipment messages Error message Possible cause Vacuum 6.11 mbar not reached • The value of 6.11 mbar is not reached within 15 minutes with an open pressure control valve.
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Freeze-dryer Alpha 1-2 LDplus 7 Malfunctions and error correction Error message Possible cause Remedy Ice condenser temperature 20°C The ice condenser temperature rises to a non-permissible value during the freeze-drying process. The pressure control valve will close automatically in order to prevent the vacuum pump from being damaged. • Insufficient cooling. • Observe the behaviour of the refrigeration system. If necessary, inform the service department (see chapter 7.3 "Service contact").
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Freeze-dryer Alpha 1-2 LDplus 8 Maintenance and service Pos: 164 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung/ 080 Wa rtun g un d Ins tan dhalt ung == === == == === == == === == == == == @ 25\ mod _14 049 840 9570 4_6 8.d ocx @ 184 307 @ 1 @ 1 8 Maintenance and service The freeze-dryer and the accessories are subject to high mechanical stress. Thorough maintenance performed by the user extends the service life and prevents premature failure.
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Freeze-dryer Alpha 1-2 LDplus 8 Maintenance and service Pos: 169 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung/ 080 -00 10- 001 0-0 010 Eiskon dens ato rkam me r (a uß er Epsil on 2 -4) @ 2 5\m od_ 1404 984 098 898 _68. docx @ 18 434 9 @ 4 @ 1 8.1.1.1 Ice condenser chamber Before each start-up, ensure that the ice condenser chamber is free from water residues. • Open the media drain valve to drain off any liquid. Then, close the valve.
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Freeze-dryer Alpha 1-2 LDplus 8 Maintenance and service • Reinsert the valve core. • Put the freeze-dryer into operation again. If the vacuum is still insufficient, the freeze-dryer must be checked by qualified specialist personnel (see chapter 7.3 - "Service contact"). Pos: 174 /01 0 Univ ersal mod ule/L eerz eile @ 0\m od_ 120 211 624 450 0_0.
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Freeze-dryer Alpha 1-2 LDplus 8 Maintenance and service 8.1.3 Exhaust filter (oil mist separator) Please refer to the separate operating manual of the vacuum pump and the exhaust filter! NOTE The oil mist that is emitted by the vacuum pump in quantities that depend on the working pressure must be led to the outside or to an exhaust hood or similar. If this is not possible, the pump must be equipped with an exhaust filter (oil mist separator).
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Freeze-dryer Alpha 1-2 LDplus 8 Maintenance and service 8.1.5 Accessories For the care of the accessories, special safety measures must be considered as these are measures that will ensure operational safety at the same time. CAUTION Chemical reactions as well as stress-corrosion (combination of oscillating pressure and chemical reaction) can affect or destroy the metal and plastic parts. Barely detectable cracks on the surface can expand and weaken the material without any visible signs.
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Freeze-dryer Alpha 1-2 LDplus 8 Maintenance and service 8.3 Service In the event of service work that requires the removal of the panels, there is a risk of electric shock or mechanical injury. Only qualified specialist personnel is authorised to perform this service work. DANGER The freeze-dryer is subject to high mechanical stress. In order to be able to withstand this high level of stress, high-quality components were used during the production of the freeze-dryer.
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Freeze-dryer Alpha 1-2 LDplus 8 Maintenance and service 8.4 Return of defective parts Although we exercise great care during the production of our products, it may be necessary to return a unit or accessory to the manufacturer. In order to ensure the quick and economical processing of returns of freeze-dryers, rotational vacuum concentrators, spare parts, or accessories, we require complete and extensive information concerning the process.
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Freeze-dryer Alpha 1-2 LDplus 9 Disposal Pos: 194 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 90 Ents org ung/ 090 Ents org ung === == == == === == == === == == === == == === == == === == @ 2 5\mo d_1 404 984 138 903 _68. docx @ 18 451 7 @ 1 @ 1 9 Disposal Pos: 195 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 90 Ents org ung/ 090 -00 10 Entso rgu ng d er G efri ertr ockn ungs anlag e @ 25\ mod _140 498 414 112 2_6 8.doc x @ 1 845 31 @ 2 @ 1 9.
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Freeze-dryer Alpha 1-2 LDplus 10 Technical data Pos: 200 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Alph a 1 -2 LD plus/ 100 Tec hnisch e Dat en/1 00 Tec hnisch e Dat en Alp ha 1 -2 LDplus == === == == === == == === == == @ 31\ mo d_1 408 0840 934 61_ 68.
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Freeze-dryer Alpha 1-2 LDplus 10 Technical data Physical data (without vacuum pump and accessories) Dimensions - height: - width: - depth: 345 mm 315 mm Weight: approx. 28 kg Noise level according to DIN 45635: 49 dB(A) EMC according to EN 55011: Class B Heat emission: 0.51 kW min. 0.91 kW max. 460 mm (incl.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Pos: 210 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/1 10 Anh ang /011 0 Anh ang == == === == == == === == == === == == === == == === == == === == == = @ 25\m od_ 140 498 417 799 4_68 .docx @ 1 846 01 @ 1 @ 1 11 Appendix Pos: 211 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Alph a 1 -2 LD plus/ 110 An han g/0 110 -002 0 Ku rzbe dien ungs anleitu ng Alp ha 1 -2 LDplus @ 31 \mo d_1 408 084 1091 22_ 68. docx @ 20 9498 @ 2 @ 1 11.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 5 6 User interface Mains power switch Fig. 49: Front and right side of the freeze-dryer 7 8 Name plate Power supply of the pressure control valve 9 Power supply of the vacuum pump 10 Equipotential bonding screw 11 Mains connection 12 Vacuum connection 13 Connection of the vacuum sensor 14 Option: data interface for further accessories 15 Heat exchanger of the refrigeration unit Fig. 50: Rear view of the freeze-dryer Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Step-by-step instructions – shelf drying 1 Freeze the sample separately, e.g. in a deep-freeze. Ensure that the layer thickness of 1 to 2 cm is not exceeded, since otherwise the drying time needs to be extended. NOTE 2 Check the ice condenser chamber and ensure that it is completely free from water residues. 3 Close the media drain valve and install the base plate.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 16 Switch the unit on again and start the defrosting process. Ensure that no water gets into the pipe connection of the vacuum pump or vacuum sensor. CAUTION 17 Drain the defrosting water via the media drain valve on the left-hand side of the unit. To do so, connect a hose to the hose connector and collect the defrosting water in a suitable vessel. 18 Keep the freeze-dryer open (i.e.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 50°C to -54°C. The pressure decreases as a function of the ice condenser temperature. NOTE The drying time depends on the layer thickness of the sample, the solids content of the sample, and the amount of heat that is supplied during the drying process. In the case of a layer thickness of 1 cm, the freeze-drying process usually takes 24 hours. 9 Switch the vacuum pump off and aerate the drying chamber via the media drain valve or via a rubber valve.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Pos: 213 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Alph a 1 -2 LD plus/ 110 An han g/0 110 -030 Kon for mitäts erklä run g Alph a 1- 2 LDpl us @ 31\ mod _14 0808 411 076 0_6 8.do cx @ 2 095 10 @ 2 @ 1 11.2 EC declaration of conformity Pos: 214 /01 0 Univ ersal mod ule/Seit enwec hsel @ 0\m od_ 120 211 624 4312 _0. docx @ 10 5 @ @ 1 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Pos: 215 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/1 10 Anh ang /011 0-0 040 Spa nnu ngsriss - u nd Ch emik alienb estä ndigk eit Plexiglas @ 2 5\m od_1 404 984 180 960 _68. docx @ 18 464 3 @ 2 @ 1 72 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 11.3 Resistance to stress cracking and chemical influences "Plexiglas" Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 74 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 76 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 78 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 80 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 82 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 84 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 86 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix 88 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Pos: 216 /01 0 Univ ersal mod ule/Absc hnittsw echsel @ 0\ mod _12 021 245 140 62_ 0.docx @ 4 18 @ @ 1 Pos: 217 /01 0 Univ ersal mod ule/Seit enwec hsel @ 0\m od_ 120 211 624 4312 _0. docx @ 10 5 @ @ 1 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 11 Appendix Pos: 218 /01 0 Univ ersal mod ule/9 00 Gl ossa r GT La bor LDplus == == === == == === == == === == == == === == == === == == === @ 3 1\m od_ 1411 375 072 732 _68. docx @ 21 048 0 @ 1 @ 1 90 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus 12 Glossary 12 Glossary Desorption Desorption (from Latin de-sorbere, sorbere = sup up, suck in) describes a phenomenon whereby molecules are released from the surface of a solid. In order to be able to desorb, the particle must have, or be provided with, a sufficient amount of energy in order to overcome the binding energy. Eutectic point The eutectic point is the point at which a homogenous mixture (e.g.
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Freeze-dryer Alpha 1-2 LDplus Index 92 Version 11/2006, Rev. 2.
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Freeze-dryer Alpha 1-2 LDplus Index 13 Index A Aborting the warm-up phase ...................... 41 Accessories ................................... 11, 25, 60 Accident prevention ................................... 23 Active phases ............................................ 39 Aeration valve ................................ 12, 33, 65 Aeration valve, cleaning and care .............. 57 Aeration valve, malfunction ........................ 51 Ambient conditions.....................................
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Freeze-dryer Alpha 1-2 LDplus Index Fire prevention ........................................... 25 Form for the return of defective parts ......... 62 Freeze-dryer, cleaning and care ................ 56 Freeze-drying phases ................................ 17 Freeze-drying process ............................... 18 Freezing ..................................................... 18 Function keys............................................. 37 Functional and operating elements ............ 12 Fuses ..........
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Freeze-dryer Alpha 1-2 LDplus Index Pending information ................................... 39 Performance data ...................................... 64 Physical data ............................................. 65 Potential hazard to the life and health ........ 22 Potentially hazardous situation................... 22 Power failure .............................................. 50 Power rating............................................... 14 Power supply .............................................
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Freeze-dryer Alpha 1-2 LDplus Index User interface ...................................... 13, 37 UV radiation ......................................... 32, 56 Value windows ........................................... 38 Vapour pressure curve above ice ............... 16 Ventilation ............................................ 32, 53 V W Vacuum ..................................................... 43 Vacuum connection ............................. 13, 65 Vacuum pump .....................................