User's Manual

Table of contents
56
3. Position the PPC near the Pump.
4. When programming is complete, the PPC will beep and the display will
automatically return to the Time/Day screen. The message “PUMP
SUSPENDED” will be displayed. The Pump will deliver a basal rate of
approximately 0.2 U/h.
In addition to the procedure above, review with family members the proper
procedure for administering glucagon.
It is important to closely monitor blood sugar levels on refill days. During a
refill procedure, a very small amount of insulin may be deposited subcutane-
ously possibly resulting in hypoglycemia.
Adverse reactions
In clinical studies, adverse reactions associated with the Medtronic
MiniMed 2007 Implantable Insulin Pump System included hypoglycemia,
diabetic ketoacidosis, hyperglycemia, skin erosion, infection, abnormal heal-
ing, elevated anti-insulin antibodies, intestinal obstruction, post-operative dis-
comfort and pain. Malfunctions in the order of frequency and seriousness
include insulin aggregation resulting in Pump under-delivery, Catheter occlu-
sion or tissue overgrowth, early Pump battery depletion and electronic Pump
failure. Adverse events associated with the use of Aventis HOE 21 PH U-400
insulin are described in the package insert accompanying the insulin medica-
tion.
Hyperglycemia
Your Implantable Insulin Pump uses a special regular insulin, so your body
will not have any reserve of long-acting insulin. Interruption of insulin deliv-
ery (due to Pump malfunction or clogging of the Catheter) or the sudden onset
of stress (emotional upset, infection, etc.) may result in a rapid rise of blood
sugar levels, and possibly the development of diabetic ketoacidosis (DKA).
Check your blood sugar levels, and your urine for ketones, if you suspect a
high glucose level. Supplemental insulin delivered by conventional means
may be required. Establish a protocol with your doctor for rapidly identifying
and treating hyperglycemia to avoid the onset of DKA.