Liquid Handling Station Manual 8.108.
Metrohm AG CH-9100 Herisau Switzerland Phone +41 71 353 85 85 Fax +41 71 353 89 01 info@metrohm.com www.metrohm.com Liquid Handling Station Manual 8.108.8011EN 05.
Teachware Metrohm AG CH-9100 Herisau teachware@metrohm.com This documentation is protected by copyright. All rights reserved. Although all the information given in this documentation has been checked with great care, errors cannot be entirely excluded. Should you notice any mistakes please send us your comments using the address given above. Documentation in additional languages can be found on http://documents.metrohm.com.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ Table of contents Table of contents 1 Introduction 1.1 1 Description ............................................................................ 1 1.2 About the documentation ................................................... 1 1.2.1 Symbols and conventions ........................................................ 2 1.3 Safety instructions ................................................................ 3 1.3.1 General notes on safety ............................................
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ Table of contents 7.2 Optional accessories ........................................................... 26 7.2.1 Liquid Handling Station ..........................................................
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ Table of figures Table of figures Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 Overview of the instrument Liquid Handling Station (left-handed version) .................................................................................................. 5 Removing the mixing vessel ...............................................................
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 1 Introduction 1 Introduction 1.1 Description The Liquid Handling Station can be combined with sample changers equipped with a robotic arm. Depending on the swing direction, either the left-handed (6.2841.120) or the right-handed (6.2841.130) version of the Liquid Handling Station is used. The Liquid Handling Station consists of two function units: Rinsing unit The rinsing unit is equipped with a two-pipe system. The interior pipe is for rinsing the sample tube.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 1.2 About the documentation 1.2.1 Symbols and conventions The following symbols and formatting may appear in this documentation: Cross-reference to figure legend The first number refers to the figure number, the second to the instrument part in the figure. Instruction step Carry out these steps in the sequence shown.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 1 Introduction 1.3 Safety instructions 1.3.1 General notes on safety WARNING This instrument may only be operated in accordance with the specifications in this documentation. This instrument exhibited no flaws in terms of technical safety at the time it left the factory. To preserve this status and ensure non-hazardous operation of the instrument, the following instructions must be observed carefully. 1.3.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 1.3 Safety instructions Protection against electrostatic charges WARNING Electronic components are sensitive to electrostatic charges and can be destroyed by discharges. Do not fail to pull the mains cable out of the mains connection socket before you set up or disconnect electrical plug connections at the rear of the instrument. 1.3.3 Flammable solvents and chemicals WARNING All relevant safety measures are to be observed when working with flammable solvents and chemicals.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 2 Overview of the instrument 2 Overview of the instrument Liquid Handling Station in the left-handed version, complete with attachment holder for assembly on a sample changer.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3.1 Preparing the Liquid Handling Station 3 Installation The installation of the Liquid Handling Station is accomplished in three main steps. 1. 2. 3. 3.1 Preparing the Liquid Handling Station. Mounting and aligning the Liquid Handling Station on the sample changer. Defining the work positions of the sample tube for the Liquid Handling Station. Preparing the Liquid Handling Station If the Liquid Handling Station is to be used for dilutions, then it must be converted.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3 Installation Figure 2 Removing the mixing vessel 2 Unscrew the three screws connecting the main body with the support bracket and remove the entire holding mechanism. Figure 3 Removing the holding mechanism 3 Unscrew the two screws on the base of the main body and pull out the magnetic stirrer dummy.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3.1 Preparing the Liquid Handling Station Figure 4 Removing the magnetic stirrer dummy Preparing the magnetic stirrer 1 Unscrew the two screws of the magnetic stirrer (2.741.0010) and remove the clamping fastener. The clamping fastener is no longer used in this application. Figure 5 Removing the clamping fastener Installing the magnetic stirrer 1 Insert the magnetic stirrer from below into the main body and place the connection cable in the corresponding recess.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3 Installation 2 Insert the two screws and tighten them. Figure 7 Tightening the magnetic stirrer 3 Place the previously removed holding mechanism against the main body and connect the two parts with the three screws. Figure 8 Screwing on the holding mechanism 4 Mount the mixing vessel and press it all the way down. NOTE Observe the recess on the bottom rim of the mixing vessel for positioning. It must snap into the main body.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3.1 Preparing the Liquid Handling Station Figure 9 Attaching the mixing vessel 5 Fixing the connection cable in place with the cable clip. NOTE Ensure that no damage is caused to the connection cable from crushing.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3.2 3 Installation Mounting the Liquid Handling Station The Liquid Handling Station requires precise mounting and alignment in order to function properly with the entire system. CAUTION Faulty, imprecise assembly The components could become damaged during operation if assembled in a faulty and imprecise manner. ￭ ￭ Observe the assembly sequence. Observe instrument movements during setup and stop in a timely fashion if necessary.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3.2 Mounting the Liquid Handling Station Placing the Liquid Handling Station on the guide 1 Attach the Liquid Handling Station to the assembly rail (11-4) with the clamping fastener (11-3). 2 Secure the Liquid Handling Station temporarily in place with the screw (11-2). Aligning the Liquid Handling Station with the rack 1 Loosen the screws (11-1) of the base plate until you can shift the Liquid Handling Station with the support bracket.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3 Installation Aligning the Liquid Handling Station with the retaining plate 1 Loosen the screw (11-2) on the clamping fastener. 2 Slide the entire Liquid Handling Station that is on the assembly rail under the retaining plate in the direction of the arrow (see Figure 14, page 14) (14-1). Figure 13 Positioning the Liquid Handling Station The precise position is shown in the following figure.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3.3 Defining work positions 1 Figure 14 1 Alignment with the retaining plate Sample tube swing range 3 Retighten the screw (11-2) on the clamping fastener. 4 Check whether the distance to the sample rack is consistent with Figure 12 and whether the position in relation to the retaining plate (see Figure 14, page 14) is suitable. 3.3 Defining work positions The Liquid Handling Station has three positions. These work positions have to be defined in the software (e.g.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3 Installation NOTE Value settings of the angles External position These value settings are guidelines that may need to be corrected when the Liquid Handling Station is set up. Figure 15 External position - Guidelines 1 External position 1 2 External position 2 3 External position 3 4 External position 4 NOTE External position 3 + 4 External positions 3 and 4 have the same angle setting. The difference between them lies in their immersion depths (Work position).
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3.3 Defining work positions 3+4 2 1 Figure 16 External positions 1 Rinsing unit - Rinse 2 Rinsing unit - Disposal 3 Dilution unit 4 Dilution unit (standard depth) CAUTION Damage to the sample tube The External position 3 also has to be set in order to avoid a collision in case it is used. 1 Move to External position 1 (16-1). 2 Check whether the sample tube is centered over the "Rinsing unit Rinse" position.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 3 Installation 3 If necessary, correct the angle value. 4 Move to External position 2 (16-2). 5 Check whether the sample tube is centered over the "Rinsing unit Disposal" position. Figure 18 Working range - Disposal 6 If necessary, correct the angle value. 7 Move to External position 3 + 4 (16-3), (16-4). 8 Check whether the sample tube is centered precisely over the opening of the dilution unit.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 4.1 General notes 4 Operation and maintenance 4.1 General notes 4.1.1 Care The Liquid Handling Station requires appropriate care. Excess contamination of the instrument may result in functional disruptions and a reduction in the lifetime of the otherwise sturdy mechanics and electronics. Spilled chemicals and solvents should be removed immediately.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 4.2 4 Operation and maintenance Quality Management and qualification with Metrohm Quality management Metrohm offers you comprehensive support in implementing quality management measures for instruments and software. Further information on this can be found in the brochure "Metrohm Quality Management" available from your local Metrohm representative. Qualification Please contact your local Metrohm representative for support in qualification of instruments and software.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 5.1 Magnetic stirrer 5 Technical specifications 5.1 Magnetic stirrer Shift direction Counterclockwise Rotational speed 200 - 1,900 rpm 5.2 Power supply Power supply 5 - 12 V DC Power consumption ≤ 4.0 W 5.3 Interfaces and connectors The Liquid Handling Station does not have any control interfaces. It is operated and controlled via the power supply. 5.4 Ambient temperature Nominal function range +5 - +45 °C Transport and storage –40 - +70 °C 5.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 5.6 Dimensions/material Width 131 mm Height 94 mm Depth 224 mm Weight 660 g (without accessories) 5 Technical specifications Material Mixing vessel/ rinsing unit PP Holder Aluminum sheet, stove-enameled 5.7 Volume Mixing vessel, total 30 mL Mixing vessel dead volume 5 mL Rinsing unit - Rinse 3.1 mL Rinsing unit - Disposal 5.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 6 Warranty (guarantee) Metrohm guarantees that the deliveries and services it provides are free of defects in materials, design or manufacturing. The general warranty period is 36 months (exclusions below) from the date of delivery or 18 months in the event of continuous operation. The warranty remains valid on the condition that the servicing is provided by a service organization authorized by Metrohm at defined intervals and with a defined scope.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 6 Warranty (guarantee) Deficiencies arising from circumstances that are not the responsibility of Metrohm, such as improper storage or improper use, etc., are expressly excluded from the warranty. Metrohm also offers a 120 month spare parts availability guarantee and a 60 month PC software support warranty, calculated from the date on which the product is withdrawn from the market.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 7.1 Scope of delivery 7 Accessories NOTE Subject to change without notice. 7.1 Scope of delivery NOTE After receiving the instrument, check the shipment to ensure that it is complete. Check the version (order number) of your Liquid Handling Station at this time as well. Liquid Handling Station 6.2841.120 / 6.2841.130 Qty. 1 Order no. Description 6.1801.120 PVC tubing / 4 mm / 6 mm / 2 m Material: Outer diameter (mm): Inner diameter (mm): Length (m): 1 6.1808.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ Qty. 1 7 Accessories Order no. Description 6.2621.030 Hex key 4 mm Length (mm): 73 1 6.2621.140 Hex key 2.5 mm 2 6.2744.060 Threaded stopper For UNF 10/32. Stopper for IC, e.g. for the sealing of columns. Material: PP Length (mm): 21 1 8.108.8011DE Liquid Handling Station Manual, DE 1 8.108.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ 7.2 Optional accessories 7.2 Optional accessories Liquid Handling Station 6.2841.120 / 6.2841.130 Qty. Order no. Description 2.741.0010 741 Magnetic Stirrer Magnetic stirrer for sample changers. 6.2762.100 Mixing vessel for Liquid Handling Station Replacement mixing vessel for the combined rinsing and dilution stations. 6.27621.110 Cover for mixing vessel 6.2762.100 Replacement cover for the mixing vessel.
￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭ Index Index C Connection cable ..................... 10 D Dilution unit ............................... 1 Dimensions .............................. 21 E Electrostatic charge .................... 4 G GLP .......................................... 19 Guarantee ................................ 22 M Magnetic stirrer .................. 1, 6, 8 Rotational speed ................. 20 Shift direction ..................... 20 Mains voltage .............................
