Specifications
The Patent Office Journal 17/12/2010 
4519
(12) PATENT APPLICATION PUBLICATION  (21) Application No.3798/CHENP/2010 A 
(19) INDIA 
(22) Date of filing of Application :21/06/2010  (43) Publication Date : 17/12/2010 
(54) Title of the invention : BIVALENT, BISPECIFIC ANTIBODIES 
(51) International classification  :C07K 16/46 
(31) Priority Document No  :07024867.9 
(32) Priority Date  :21/12/2007 
(33) Name of priority country 
:EUROPEAN 
UNION 
(86) International Application No 
 Filing Date 
:PCT/EP08/010702
:16/12/2008 
(87) International Publication No 
:WO 2009/080251 
A1 
(61) Patent of Addition to Application Number 
 Filing Date 
:NA 
:NA 
(62) Divisional to Application Number 
 Filing Date 
:NA 
:NA 
(71)Name of Applicant : 
 1)F.HOFFMANN-LA ROCHE AG 
 Address of Applicant :GRENZACHERSTRASSE 124, CH-
4070, BASEL Switzerland 
(72)Name of Inventor : 
 1)KLEIN, CHRISTIAN 
 2)SCHAEFER, WOLFGANG 
(57) Abstract : 
The present invention relates to novel domain exchanged, bivalent, bispecific antibodies, their manufacture and use. 
No. of Pages : 126 No. of Claims : 10 










