Specifications

The Patent Office Journal 17/12/2010
4552
(12) PATENT APPLICATION PUBLICATION (21) Application No.3958/CHENP/2010 A
(19) INDIA
(22) Date of filing of Application :25/06/2010 (43) Publication Date : 17/12/2010
(54) Title of the invention : AMINO ACID SEQUENCES DIRECTED AGAINST HETERODIMERIC CYTOKINES AND/OR
THEIR RECEPTORS AND POLYPEPTIDES COMPRISING THE SAME
(51) International classification :C07K16/24
(31) Priority Document No :61/004,332
(32) Priority Date :27/11/2007
(33) Name of priority country :U.S.A.
(86) International Application No
Filing Date
:PCT/EP08/066365
:27/11/2008
(87) International Publication No
:WO/2009/068627
A3
(61) Patent of Addition to Application Number
Filing Date
:NA
:NA
(62) Divisional to Application Number
Filing Date
:NA
:NA
(71)Name of Applicant :
1)ABLYNX N.V.
Address of Applicant :TECHNOLOGIEPARK 4, 9052
GHENT-ZWIJNAARDE Belgium
(72)Name of Inventor :
1)SAUNDERS, MICHAEL, JOHN, SCOTT
2)BLANCHETOT, CHRISTOPHE
3)ROMMELAERE, HEIDI
4)VERCAMMEN, JO
5)DE HAARD, JOHANNES, JOSEPH, WILHELMUS
(57) Abstract :
The present invention relates to amino acid sequences that are directed against (as defined herein) heterodimeric cytokines and/or their
receptors, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of
one or more such amino acid sequences (also referred to herein as amino acid sequences of the invention, compounds of the invention
and polypeptides of the invention, respectively). The invention also relates to nucleic acids encoding such amino acid sequences and
polypeptides (also referred to herein as nucleic acids of the invention or nucleotide sequences of the invention); to methods for
p
reparing such amino acid sequences and polypeptides; to host cells expressing or capable of expressing such amino acid sequences or
polypeptides; to compositions, and in particular to pharmaceutical compositions, that comprise such amino acid sequences,
polypeptides, nucleic acids and/or host cells; and to of such amino acid sequences or polypeptdies, nucleic acids, host cells and/or
positions, in particular for prophylactic, therapeutic or diagnostic purposes, such as the prophylactic, therepeutic or diagnostic
purposes mentioned herein.
No. of Pages : 1438 No. of Claims : 30