Specifications

The Patent Office Journal 17/12/2010
4436
(12) PATENT APPLICATION PUBLICATION (21) Application No.1640/CHE/2010 A
(19) INDIA
(22) Date of filing of Application :14/06/2010 (43) Publication Date : 17/12/2010
(54) Title of the invention : PROCESS FOR THE PREPARATION OF GABAPENTIN
(51) International classification :C07C227/00
(31) Priority Document No :NA
(32) Priority Date :NA
(33) Name of priority country :NA
(86) International Application No
Filing Date
:NA
:NA
(87) International Publication No : NA
(61) Patent of Addition to Application Number
Filing Date
:NA
:NA
(62) Divisional to Application Number
Filing Date
:NA
:NA
(71)Name of Applicant :
1)DIVI'S LABORATORIES LTD.,
Address of Applicant :7-1-77/E/1/303; DIVI TOWERS;
DHARAM KARAN ROAD; AMEERPET; HYDERABAD - 500
016. Andhra Pradesh India
(72)Name of Inventor :
1)MURALI KRISHNA PRASAD DIVI
2)GUNDU RAO PADAKANDLA
3)MYSORE ASWATHA NARAYANA RAO
4)SHAIK NOWSHUDDIN
5)MADDIPATI PRASAD
(57) Abstract :
This invention discloses a process for converting gabapentin acid salt to free gabapentin, where the salt is dissolved in an organic
solvent in which both gabapentin acid salt and free gabapentin are soluble. The solution is treated with a powdered alkaline base to
liberate free gabapentin which will remain in solution. The insoluble alkali salt of the acid is removed by filtration. From the filtrate
free gabapentin is obtained either by adding anti-solvent or by extraction with water.
No. of Pages : 12 No. of Claims : 10