Specifications

The Patent Office Journal 17/12/2010
4598
(12) PATENT APPLICATION PUBLICATION (21) Application No.3990/CHENP/2010 A
(19) INDIA
(22) Date of filing of Application :28/06/2010 (43) Publication Date : 17/12/2010
(54) Title of the invention : TREATMENT OF CANCER WITH COMBINATIONS OF TOPOISOMERASE INHIBITORS AND
PARP INHIBITORS
(51) International classification :A01N43/42
(31) Priority Document No :61/012,364
(32) Priority Date :07/12/2007
(33) Name of priority country :U.S.A.
(86) International Application No
Filing Date
:PCT/US08/085756
:05/12/2008
(87) International Publication No
:WO 2009/073869
A1
(61) Patent of Addition to Application
Number
Filing Date
:NA
:NA
(62) Divisional to Application Number
Filing Date
:NA
:NA
(71)Name of Applicant :
1)BIPAR SCIENCES INC
Address of Applicant :400 OYSTER POINT
BOULEVARD,SUIT 200 SOUTH SAN
FRANCISCO,CALIFORNIA 94080. U.S.A.
(72)Name of Inventor :
1)OSSOVSKAYA VALERIA S
2)BRADLEY CHARLES
3)SHERMAN BARRY M
(57) Abstract :
In one aspect, the present invention provides a composition and a kit comprising a combination o topoisomerase inhibitor and PARP
inhibitor for treatment of cancer. In another aspect, the invention provides a method of treating cancer comprising administering to a
subject a combination o topoisomerase inhibitor and PARP inhibitor. In particular, the invention provides compositions and methods
for treating cancer in a subject by inhibiting a poly-ADP-ribose polymerase and a topoisomerase, as well as providing formulations
and modes of administering such compositions.
No. of Pages : 62 No. of Claims : 21