SDS

ManualsBrandsNasacort ManualsAllergy & Sinus24 Hour Allergy Relief Spray - 120 Sprays

1. Product and Company Identification

PRODUCT NAME: NASACORT® AQ (triamcinolone acetonide)

Nasal Spray

Substance name: Triamcinolone acetonide

Supplier:

Sanofi-aventis U.S. LLC

A SANOFI COMPANY

55 Corporate Drive

Bridgewater, NJ 08807

24-Hour Transport Emergency, US (Chemtrec): (800) 424-9300

24-Hour Transport Emergency, outside US (Chemtrec): (703) 527-3887

US Customer Service (800) 207-8049

24-Hour Emergency, sanofi-aventis US: (908) 981-5550

Product use: Pharmaceutical product.

2. Hazards Identification

2.1 Classification in accordance with 29 CFR 1910.1200

Classification: Not classified as a hazardous mixture.

2.2 Label elements in accordance with 29 CFR 1910.1200

Labeling of the finished drug product is not required according to OSHA 29 CFR 1900.1200.

The following information is provided for the product mixture:

Signal Word: None required.

Hazard Statement(s): None required.

Symbol(s): None required.

Summary of content (10 pages)

PAGE 1
. Product and Company Identification PRODUCT NAME: NASACORT® AQ (triamcinolone acetonide) Nasal Spray Substance name: Triamcinolone acetonide Supplier: Sanofi-aventis U.S. LLC A SANOFI COMPANY 55 Corporate Drive Bridgewater, NJ 08807 24-Hour Transport Emergency, US (Chemtrec): 24-Hour Transport Emergency, outside US (Chemtrec): US Customer Service 24-Hour Emergency, sanofi-aventis US: (800) 424-9300 (703) 527-3887 (800) 207-8049 (908) 981-5550 Product use: Pharmaceutical product. 2.
PAGE 2
Precautionary Statement(s):  Prevention: None required.  Response: None required.  Storage: None required.  Disposal: None required. 2.3 Hazards Not Otherwise Classified (HNOC) Not classified. 3. Composition/Information on Ingredients Chemical Name: Common Name: CAS #: 9-Fluoro-11β,16α,17,21tetrahydroxypregna-1,4-diene3,20-dione cyclic 16,17-acetal with acetone Triamcinolone acetonide (TAA) 76-25-5 Percentage or concentration range 0.
PAGE 3
Inhalation: If product is inhaled, remove to fresh air. If breathing is difficult, trained personnel should give oxygen. Get medical attention. 4.2 Most important symptoms and effects, both acute and delayed Most common adverse reactions (>2% incidence) were pharyngitis, epistaxis, flu syndrome, cough increased, bronchitis, dyspepsia, tooth disorder, headache, pharyngolaryngeal pain, nasopharyngitis, abdominal upper pain, diarrhea, and excoriation. 4.
PAGE 4
6. Accidental Release Measures 6.1 Personal precautions and Protective Equipment: Eye protection, respiratory protective equipment, and suitable protective clothing should be worn (see Section 8). 6.2 Emergency Procedures: Follow local workplace procedures. Prevent the product from entering the environment. Avoid discharges to sewers, drains, waterways, or onto the ground. 6.
PAGE 5
8. Exposure Controls/Personal Protection 8.1 Exposure Limits Sanofi-aventis occupational exposure limit, triamcinolone acetonide: 0.001 mg/m3, 8-hour TWA. 8.2 Appropriate Engineering Controls Provide adequate ventilation. No other specific controls are needed under normal handling conditions. 8.3 Individual Protection Measures Eye/face protection: Safety glasses or safety goggles should be worn if there is a potential for eye contact with the product.
PAGE 6
Partition coefficient: n-octanol/water (triamcinolone acetonide): Log Kow = 2.53 (experimental). Auto-ignition temperature: no data available. Decomposition temperature: no data available. Viscosity: no data available. 10. Stability and Reactivity 10.1 Reactivity Not a reactive material under normal handling conditions. 10.2 Chemical Stability Stable under normal handling conditions. 10.3 Possibility of hazardous reactions None known. 10.
PAGE 7
Symptoms related to the physical, chemical and toxicological characteristics: Pharyngitis, epistaxis, flu syndrome, cough increased, bronchitis, dyspepsia, tooth disorder, headache, pharyngolaryngeal pain, nasopharyngitis, abdominal upper pain, diarrhea, and excoriation. Effects of short-term (acute) exposure: Harmful if swallowed. Effects of long-term (chronic) exposure: Causes damage to organs (endocrine system) through prolonged or repeated exposure.
PAGE 8
12. Ecological Information The following information is for the active ingredient triamcinolone acetonide unless otherwise noted: 12.1. Ecotoxicity Toxicity on invertebrates: (EC50): > 100 mg/l Species: Daphnia magna Duration of exposure: 48 h Method: Tested according to OECD 202. Algae toxicity (EC50): > 10 mg/l Duration of exposure: 72 h Method: OECD 201 12.2. Persistence and degradability Biological degradability: 4.
PAGE 9
13.2 Disposal of packaging waste Dispose of in a safe manner in accordance with federal, state and local environmental regulations. Empty packages, containers or liners may contain product residue. 14. Transport Information 14.1 Basic shipping information, finished product U.S. DOT ICAO/IATA IMDG Not a regulated material. Not a regulated material. Not a regulated material. 15. Regulatory Information US Regulations CERCLA Hazardous Substance List (40 CFR 302.4): Not listed.
PAGE 10
Abbreviations and Acronyms CAS: Chemical Abstracts Service DOT: U.S. Department of Transportation EST: Eastern standard time (U.S.) IATA: International Air Transport Association IMDG: International Maritime Dangerous Goods Code LC50: Lethal concentration, 50% LD50: Lethal dose, 50% OEL: Occupational Exposure Limit PPE: Personal Protection Equipment SDS: Safety Data Sheet STEL: Short-term exposure limit TWA: Time-weighted average U.S.: United States Date Prepared : January 4, 2015 First version.