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

Summary of content (40 pages)

PAGE 1
! ɊɍɄɈȼɈȾɋɌȼɈ ɉɈ ɗɄɋɉɅɍȺɌȺɐɂɂ "# $% " & "' #( %)
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* * ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++, ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ ' - .
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# . ,)( /) ( 4 45 % 0 & $ ))" 6 ( ) ) # 4 45 % /( , ( )$ 2 ))" ( $) ) 7 ) ) ) )$ $ ( ,)( 2 ))" ( " ( $ , " 8( .
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' - .
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49 9 * 0+ 12 2 A E D B C & ! , 4 #& # 2( ) + 4 > 2( ) ! # 2( ) F G , )$ $ 1 & ' . A &+ " ' .
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49 9 * * - / ) .
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49 9 * .
PAGE 8
6 ) ,+ ,+0 =% 0+ #( $ ( ( " ")* ,+ " 2 , )9 " ) )/ )* * 22 " )/ )9 + ) /)( :&&; F 2 ) I < ) 9 = " < 9 = ) $ ) " " ) 2 , )$ $ /+ 6( 2 , )9 2 . " 2 , )9 " "7 ( .
PAGE 9
6 ) / 2 , )* ,$2) < = ) " ,7 /)( 2 $ $ - 2 , )* ,$2) < = ) 2 .
PAGE 10
6 ) ,+, ' & >)( 2 ))" ( $) ) ( )$ , ) ( ) $ ( $ 9 ( $ $) , " ( 9 9 ( 2 " ) $) $ ( $ . * $ ( )/ " < / ) , *) " $ $) , /) )"7 9 * 2 2 " ) *) " / ) , ) " $ $) , /) )"7 " * 2 " , " 9 9 ( = #) $ .
PAGE 11
6 ) + 6 # 2( ) ) ) / $ * " " ($2 ) " , # , " $) " / ) " , /+ " % ) $) # $) " " , " / ) " , 3+ " % ) " , # " , " )( " / ) " , "#
PAGE 12
6 ) 6+ " % ) )( # )( " $ ( " / ) " , 8+ " % ) $ ( # $ ( # ( ( )$ , ( / )// / $ ( 2 #) "'( " " $ 7 2( ) * $) ) "2, $)"
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6 ) ,+ ! ' >)( $)" /, ) ) /) 9 )( )/ ,)( ( # ") 2, # 2( ) ) 7 4 > 2( ) ) ) ) /) &/ 7 4 #& # 2( ) ) ) / $ " ( )* )// - (FF $)" ) 7 ( $ )( " 7 "( $ ( $ 7 " * $ ( $ )$ 0+ 6 # 2( ) ) * (
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% 0 0 + ) ) +0 7 ' * . > & >)( . $ ( $ ) ,)( / ) $ # < ? ( $ )( " 2 . 8( " ,)( )( " 2 @ "7 " ) ) . ( ))$ ) )) ) ) ) " ? !) ) . $ ( $ / 2 7 " . ) ) 7 ) @ ? !) ) $)9 ) . "( $ ( $ * ' . + % 2 - - .
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% 0 0 # < ? +) ) ( "( $ ( $ , ) ( ( ? >)( )( " ) , ) $ ( ,)( 2 ))" ( $ $ " , <- )( / * . ( )$$ " " = ? @ - A ? ' B ? ' - .
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% 0 0 +, . * -- ( ) * $ (// ) , ) ,)( ( ( ( $ 2 . ) )* 9 7 $)9 . ) 7 ( * 7 2 /) . " 0+ ( ) ' .
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% 0 0 + 6) ) $ ) , = # (2 )( " ( ")* " )/ ,)( /) $ " 2 * ,)( $ "" / = # 2) )$ )/ (// )( " 2 )@ $ , ) $ 2)9 ,)( 2)* %= & , (// ) ,)( ( $ ) ) )( " $ .
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% 0 0 + & % 0+ 6 4 #& # 2( ) ) ( ) ( * ,)( / / ) / )) " ,)( $ ) 2 ) (// * 2 $ 9 ,)( D " ") ) .
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% 0 0 ,+ + . $ ( $ ( # ( ( )$ , ) 2 ))" ( " ( ) $ $) , / ) :% 0 $) , 1( ) ; , ) 2 ))" ( ! ) 2 ))" ( 6( " , # 2(FF * )( " * $ ( $ )$ " # < ? / " ) )/ $ ( " ( " $ " )( 6 /) )* ( ) )/ ,)( ") ) ? - % $ ( 2 /) .
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% 0 0 ? >)( 2 ))" ( $) ) (" ( 2 / ( ( 2 / ( ( )/ $ ( $ # ( 2 ) $ ( )$ , " $ / $ ( $ ( 2 ) " ) 2 " / $ ( $ ( // " 2, ( 2 2( ( 9 "7 ( )* ) * ( 2 ) / ( 2 ( $ ( $ ) 2 9 "7 ) ( )
PAGE 21
% 0 0 > . C & 2 $( " 2, ( ) ) & , $ ) " ) * 2 , $ 2 ) $ "( ) / * 2 ) , $ " 9 2 #, ,$ )$ . " 2 7 $ ( ) ) 7 2 ) $ , " < , " = ) )* <2 ", " = ( # 2 ( " 2, " 7 7 , " ) ) 7 7 .
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% 0 0 +/ - / ,)( , ) ( . )* ) 2 $) $$ 7 " ) " 4 #& # 2( ) ( $ (// / % ) $$ ,)( ( " , ) ( 0+ 6 4 #& # 2( ) ) ( ( ) ( $ ,+ - (// ) / 7 4 #& # 2( ) " .
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% 0 0 +3 ) .
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% 0 0 ,+ 6 4 > 2( ) 7 * 9 9 ( " , " # ( / )$ $) $ ( $ " , " # " " $ )/ $ ( $ " , " , * $ ( $ 9 ( < / ,)( , ) ) " ) ( )( " " " 7 2 ,$2) * 2 .
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% 0 0 ! " # $ >)( ) " " 9 "( ) " " 7 " ( * 2 " " 0+ #) " ) " " 7 / 4 > 2( ) # * ) " ")* 7 4 #& # 2( ) $( )( , /) 2)( % ) " & " * 2 " " < /( ) ) 4 #& # 2( ) / / 4 #& # 2( ) " / 7 $ ( $ * ,+ 6 4 #& # 2(
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G( . / A( " /+ 5 % - / ,)( ( " 9 /) / $ 7 " /( , % )/ ( ) $ ( #) ( 2 " 7 9) " 7 $). 7 ) @ /) % $ ( 2 /) .
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" ) " 6 )2 $ 3+ 7 " 3+0 " " . * % . +(// ( " / " + /( , " " " ( " ) % )9 $ "( $ ( $ $ ( $ $ " ") ) .
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" ) " 6 )2 $ " . * ! 9 ) % .
PAGE 29
" ) " 6 )2 $ 3+, & * % . & $ (// ) " ) , & , $ (// ) , / ) ) % )9 $ ) . "( $ ( $ $ " ") ) . "( $ ( $ / ) ) % % + ) / * $ (// $)9 , ) / * $ (// / ) ) % ' . ( , " ) $ ( K . ( ' .
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" ) " 6 )2 $ 4 )2 $ % * % .
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" ) 6+ ' #) ) ,)( ( / )$ " $ 7 )2 9 /) )* B ? !) ) (2' $ ( " (// ) @ $ $ ( 7 ($ " ,7 $) ( ) " ( ? !) ) /) " (// ) (2 , ? !) ) / $ (// )9 33 $$ ? !) ) " $2 ( ? !) ) (2' ( ) ) ) .
PAGE 32
" ) * ' 2 ? # ( , )/ 2 ))" ( $) ) 2 /( , " " " " /) ) 9 / ? , )$$ " " ) 9 ( " 9 , *) , ) ( ) /( ) " ( , 6 ) ( ,)( ( ) " 4 45 " ) 4 45 +( )$ 9 "" 9 ) .
PAGE 33
" ) ' D ( ) * ) ( 0+ 0 ( (2 / )$ ' . ,+ A , /) " (2 ) $ (// # < !) ) 2 " (2 @ 9 , + 6 $ (// " $ ( ) !) ) ) ( /) )* ( ) B ? / ( * ? E) ) @ ) " ) @ $ $ ( 7 ($ " ,7 " ( 7 "( ) ) ) 9 9 )( ? E) ) @ ) " ) 9 2 ) 7 ) .
PAGE 34
4 ) 6 8+ 1 * -- & $ ($/ ( * -- % $ & $ ($/ % $ * D5E + 33 +E 33 + 3% G &" 3 %% ) 1 * 2 ) 2 , )$ $ 9 * ( &+ " # < ? 5 9 ( ( )* ) " * * " ? 0 ) , ) &+ " " " /) ( 0 )/ ( ( ) " " $ , " $ ( ? - ) ) ) &+ "
PAGE 35
# ! 4+ & . % . . - - ' . - 1 = 7 . ' 7 * * 1 .
PAGE 36
# ! # % $ & '%$&( - " ($2 )/ ) " 9 ( 6+N " $)2 < ( = ) 7 $ " " 9 ( $ , 2 ( 2 ) )$ / / )$ ) " 9 )$ / $ , ( ) ) ) )/ $ " " 9 " ) , ( / ( ) " " 9 )( " ) ) / * ) " 9 ) " ) ( 8( $ /)
PAGE 37
3 )$ 0 /( /) $ ) 2)( ))" 6 ( 9+ ' ) - - # ) ))" ( $ ( )/ /) )/ 2 ))" / )* * )/ & 2 ))" ( ) , "( )( )/ O , # ( , " P )* ) ( " 7 " 7 , ) 2 ") ) ) 9 (
PAGE 38
3 )$ 0 /( /) $ ) 2)( ))" 6 ( Upper curve: systolic blood pressure Lower curve: diastolic blood pressure 200 mmHg 150 100 50 6 12 18 24 Time of day Example: fluctuation within a day (male, 35 years old) & # ) # , - # -) " 4 F ) <- 4= " ) ) , )/ , ) < = " 9 ) " ))" 6 ( + / ) )* / ( Systolic blood pressure (mmHg) Severe hypertension 180 Modera
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3 )$ 0 /( /) $ ) 2)( ))" 6 ( - 1 %1# 7" (&7* %" *1+: (& + 7 > $ )( > $ ) )7 0.,) .(7 D,) )7 7 C ")B 2 1 %1# 7" (&7* %" ")%1 " +F+ D ( * 7 % 5& ))/"") 7 # 5 " *** )$ ) )$ - . EC REP 1 %1# ( # *1+: (& + ) )$ R # ! 9 ) $ S) ! 7 + 1 %1# 7" (&7* %" )G (& + 4 ! 9 1)@ 7 ) D , D !A7 0 " D ")$ ' .
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3 )$ 0 /( /) $ ) 2)( ))" 6 (