SDS

SDS 672
PRESTONE® EXTENDED LIFE HEAVY DUTY
ANTIFREEZE/COOLANT (YELLOW OAT) PRE-DILUTED 50%
Date Prepared: 08/05/2016
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Response:
P301 + P312 IF SWALLOWED: Call a POISON CENTER or physician if you feel unwell.
P330 Rinse mouth.
P308 + P313 IF exposed or concerned: Get medical advice.
Disposal:
P405 Store locked up.
P501 Dispose of contents and container in accordance with local and national regulations.
3. Composition/Information on Ingredients
Component CAS No. Amount
Ethylene Glycol 107-21-1 45-55
Water 7732-18-5 45-55
2-Ethyl Hexanoic Acid, Sodium Salt 19766-89-3 1-5
Diethylene Glycol 111-46-6 0-5
The exact concentrations are a trade secret.
4. First Aid Measures
INHALATION: Remove the victim to fresh air. If breathing has stopped administer artificial respiration. If breathing is
difficult, have medical personnel administer oxygen. Get medical attention.
SKIN CONTACT: Remove contaminated clothing. Immediately wash contacted area thoroughly with soap and water. If
irritation persists, get medical attention.
EYE CONTACT: Immediately flush eyes with large amounts of water for 15 minutes. Get medical attention if irritation
persists.
INGESTION: Seek immediate medical attention. Immediately call local poison control center or go to an emergency
department. Never give anything by mouth to or induce vomiting in an unconscious or drowsy person.
MOST IMPORTANT SYMPTOMS: May cause eye irritation. Inhalation of mists may cause nose and throat irritation and
nervous system effects. Ingestion may cause abdominal discomfort or pain, nausea, vomiting, dizziness, drowsiness, malaise,
blurring of vision, irritability, back pain, decrease in urine output, kidney failure, and central nervous system effects.
INDICATION OF IMMEDIATE MEDICAL ATTENTION AND SPECIAL TREATMENT, IF NEEDED: Seek immediate
medical attention for large ingestions.
NOTES TO PHYSICIAN: The principal toxic effects of ethylene glycol, when swallowed, are kidney damage and metabolic
acidosis. The combination of metabolic acidosis, an osmol gap and oxalate crystals in the urine is evidence of ethylene glycol
poisoning. Pulmonary edema with hypoxemia has been described in a number of patients following poisoning with ethylene
glycol. Respiratory support with mechanical ventilation may be required. There may be cranial nerve involvement in the late
stages of toxicity from swallowed ethylene glycol. In particular, effects have been reported involving the seventh, eighth, and
ninth cranial nerves, presenting with bilateral facial paralysis, diminished hearing and dysphagia.
Ethanol is antidotal and its early administration may block the formation of nephrotoxic metabolites of ethylene glycol in the
liver. The objective is to rapidly achieve and maintain a blood ethanol level of approximately 100 mg/dl by giving a loading
dose of ethanol followed by a maintenance dose. Intravenous administration of ethanol is the preferred route. Ethanol blood
levels should be checked frequently. Hemodialysis may be required. 4-Methyl pyrazole (Fomepizole®), a potent inhibitor of
alcohol dehydrogenase, has been used therapeutically to decrease the metabolic consequences of ethylene glycol poisoning.
Fomepizole® is easier to use clinically than ethanol, does not cause CNS depression or hypoglycemia and requires less
monitoring than ethanol. Additional therapeutic modalities which may decrease the adverse consequences of ethylene glycol