SDS

SAMSUNG SDI Co., Ltd.
Date: Jan 7
th
2020 Revision no.: 01
ELG(P11P35-11-N01,3.7L1200SPA)
Page 14 of 22
- Carbon black : Present
- Nickel : Present
ACGIH
- Cobalt and cobalt compounds : A3
- Aluminum : A4
- Carbon black : A3
- Nickel : A5
- Manganese : A4
KOREA-ISHL
- Cobalt and inorganic compounds : 2
- Carbon black : 2
- Nickel : 1A
EU
- Nickel : Carc. 2
Cobalt hydroxide oxide : Carcinogenicity studies using rats (male / female) revealed carcinogenic
effects.(OECD Guideline 451, GLP)
Copper : EPA IRIS: D In carcinogenicity study with rat, tumor was not observed.
Tricobalt tetraoxide : Under the conditions of these 2-year inhalation studies, there was some evidence
of carcinogenic activity of cobalt sulfate heptahydrate in male F344/N rats based on increased
incidences of alveolar/bronchiolar neoplasms.(GLP)
Polyethylene : Fifty rats were implanted with polyethylene. In the polyethylene group, 23 developed
tumors (two of these were unrelated to the implants).
Carbonic acid diethyl ester : In long-term oral toxicity with mice,the incidence of histological lesions,
including tumours of the ovaries was not influenced by treatment with the test substance.
Carbon black : Most of the tumours were benign squamous cysts, but a high incidence of
adenocarcinoma was also found in all groups. (OECD Guideline 451)
Mutagenicity :
- Cobalt hydroxide oxide : Negative reactions were observed in vitro Bacterial Reverse Mutation
Assay(OECD Guideline 471, GLP). Negative reactions were observed in vivo Mammalian Bone
Marrow Chromosome Aberration Test(OECD Guideline 475).
- Graphite : Negative reactions were observed in vitro (Bacterial Reverse Mutation Assay(OECD
Guideline 471, GLP)).
- Aluminum : Negative reactions were observed in vitro (mammalian cell gene mutation assay with
mouse lymphoma L5178Y cells(OECD TG 476, GLP)) and in vivo (micronucleus assay with rats
(OECD TG 474, GLP)). (Aluminium hydroxide, aluminium chloride, aluminum oxide; read across)
- Lithium carbonate;Lithane : Negative reactions were observed in vitro (Bacterial Reverse Mutation
Assay(OECD Guideline 471, GLP)).
- Copper : Negative reactions were observed in both in vitro(Ames test) and in vivo(DNA damage
and/or repair; unscheduled DNA synthesis, micronucleus assay). (GLP)
- Ethyl methyl carbonate : Negative reactions were observed in vitro (Mammalian Chromosome
Aberration Test(OECD Guideline 473, GLP)).
- Tricobalt tetraoxide : Negative reactions were observed in vitro mammalian cell gene mutation
test(OECD TG 476), mammalian cell micronucleus test and in vivo mammalian chromosome
aberration assay(OECD 475).
- 1,3-Dioxolan-2-one : Negative reactions were observed in vitro (mammalian cell gene mutation
assay (OECD Guideline 476, GLP)).
- Polyethylene : Negative reactions were observed in Ames test using Salmonella typhimurium and