MSDS

Dermal LD50 6,700 mg/kg (rat)
FOR CALCIUM CARBONATE: Oral LD50 – 7,340 mg/kg (rat)
FOR CALCIUM OXIDE: Not established.
FOR TITANIUM DIOXIDE: Inhalation TCLo – 250 mg/m
3
/6hr (rat)
Oral LD50 >24,000 mg/kg (rat)
Dermal LD50 >10,000 mg/m
3
(rabbit)
FOR XYLENE: Inhalation LC50 – 5,000 ppm/4hr (rat)
Oral LD50 4,300 mg/kg (rat)
Dermal LD50 >1,700 mg/kg (rabbit)
FOR MDI: Inhalation LC50 178 mg/m
3
(rat)
Oral LD50 2,200 mg/kg (mouse)
FOR ETHYL BENZENE: Oral LD50 – 3,500 mg/kg (rat)
Dermal LD50 17,800 µL/kg (rabbit)
Inhalation LCLo 4,000 ppm/4hr (rat)
FOR SILICA, QUARTZ: Implant TDLo – 900 mg/kg (rat)
Inhalation TCLo 300 µg/m
3
(human)
Intravenous LDLo 40 mg/kg (mouse)
CHRONIC TOXICITY:
SKIN: Repeat contact with skin may cause severe irritation, sensitization, or allergic
reaction. Prolonged skin contact with xylene or ethyl benzene may cause skin
irritation or dermatitis. Chronic exposure to calcium oxide may cause severe
corrosive damage.
INHALATION: Vapor overexposure may cause drowsiness, irritate eyes, nose, and throat, or
injure blood, liver, or central nervous system. Prolonged inhalation of dust
(including calcium carbonate, titanium dioxide, and silica in dust form) may cause
respiratory effects including shortness of breath, reduced pulmonary function, and
pulmonary fibrosis (scarring of the lungs). Chronic exposure to BBP by inhalation
may cause sleepiness, withdrawal and weight loss or decreased weight gain.
Chronic exposure to xylene may cause damage to the eyes, central nervous
system, bone marrow, liver, or kidneys. Chronic inhalation of calcium oxide may
cause inflammation and ulcers in the respiratory system. Chronic overexposure to
isocyanates (found in MDI) may cause lung damage and isocyanate sensitization
(chemical asthma), which may be temporary or permanent. Chronic inhalation of
ethyl benzene may have central nervous effects.