SDS
Safety Data Sheet
ReMARKable Water Based Dry-Erase –Hardener Part A
Revision date: 2018/06/14
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Guinea pig maximization test Species: guinea pig
Result: sensitizing
Sensitizing effect in animal tests
Aspiration Hazard
No aspiration hazard expected.
Chronic Toxicity/Effects
Repeated dose toxicity
Assessment of repeated dose toxicity: Based on available Data, the classification criteria are not met.
Symptoms of Exposure
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section
11.
Toxicity Data for Homopolymer of Hexamethylene Diisocyanate
Toxicity Note
Data is based on a similar product, including residual monomer.
Acute Oral Toxicity
LD50: > 5000 mg/kg (rat, female) (OECD Test Guideline 423) Toxicological studies at the product
Acute Inhalation Toxicity
LC50: 0.39 mg/1, 4 h (rat, female) (OECD Test Guideline 403)
Toxicological studies of a comparable product. The test atmosphere generated in the ani1nal study is not
representative of workplace environments, how the substance is placed on the 1narket, and how it can
reasonably be expected to be used. Therefore the test result cannot be directly applied for the purpose of
assessing hazard. Based on the weight of the evidence, a modified classification for acute inhalation toxicity is
justified.
Acute Dermal Toxicity
LD50: > 2000 mg/kg (rat, male/female) (OECD Test Guideline 402) Studies of a comparable product.
LD50: > 2000 mg/kg (rabbit, male/female) Studies of a comparable product.
Skin Irritation
rabbit, OECD Test Guideline 404, slight irritant Toxicological studies at the product
Eye Irritation
rabbit, OECD Test Guideline 405, slight irritant Toxicological studies at the product
Sensitization
Skin sensitization (local lymph node assay (LLNA)) : Causes sensitization. (mouse, OECD Test Guideline 429)
Toxicological studies at the product
Respiratory sensitization: sensitizer Studies of a comparable product.
Repeated Dose Toxicity
90 d, Inhalant: NOAEL: 3,3, (rat, male/female, 6 hours a day, 5 days a week)
Toxicological studies of a co1nparable product. Evidence of damage to organs other than the organs of
respiration was not found.
Mutagenicity