MSDS

Monsanto Company, Lawn & Garden Products
Page: 6 / 9
Roundup® Ready-To-Use Weed & Grass Killer III
Version: 2.0
Effective date: 08/21/2013
Moderate irritation.
FIFRA category III.
N-(phosphonomethyl)glycine; { glyphosate}
Mutagenicity
In vitro and in vivo mutagenicity test(s):
Not mutagenic.
Repeated dose toxicity
Rabbit, dermal, 21 days:
NOAEL toxicity: > 5,000 mg/kg body weight/day
Target organs/systems: none
Other effects: none
Rat, oral, 3 months:
NOAEL toxicity: > 20,000 mg/kg diet
Target organs/systems: none
Other effects: none
Chronic effects/carcinogenicity
Rat, oral, 24 months:
NOAEL toxicity: ~ 8,000 mg/kg diet
Target organs/systems: eyes
Other effects: decrease of body weight gain, histopathologic effects
NOEL tumour: > 20,000 ppm
Tumours: none
Toxicity to reproduction/fertility
Rat, oral, 2 generations:
NOAEL toxicity: 10,000 ppm
NOAEL reproduction: > 30,000 mg/kg diet
Target organs/systems in parents: none
Other effects in parents: decrease of body weight gain
Target organs/systems in pups: none
Other effects in pups: decrease of body weight gain
Effects on offspring only observed with maternal toxicity.
Developmental toxicity/teratogenicity
Rat, oral, 6 - 19 days of gestation:
NOAEL toxicity: 1,000 mg/kg body weight
NOAEL development: 1,000 mg/kg body weight
Other effects in mother animal: decrease of body weight gain, decrease of survival
Developmental effects: weight loss, post-implantation loss, delayed ossification
Effects on offspring only observed with maternal toxicity.
Rabbit, oral, 6 - 27 days of gestation:
NOAEL toxicity: 175 mg/kg body weight
NOAEL development: 175 mg/kg body weight
Target organs/systems in mother animal: none
Other effects in mother animal: decrease of survival
Developmental effects: none
Pelargonic and related fatty acids
Repeated dose toxicity
Rat, oral, 4 weeks:
Dosage: 2,090 mg/kg body weight/day
Target organs/systems: none
Other effects: none
12. ECOLOGICAL INFORMATION