MSDS

Monsanto Company, Lawn & Garden Products
Page: 5 / 10
Roundup® Ready-To-Use Extended Control Weed & Grass
Killer Plus Weed Preventer II
Version: 1.0 Effective date: 11/21/2006
This section is intended for use by toxicologists and other health professionals.
Data obtained on product, similar products and on components are summarized below.
Eye irritation
Rabbit, 3 animals, OECD 405 test:
Days to heal: 14
Moderate irritation.
FIFRA category III.
Similar formulation
Acute oral toxicity
Rat, LD50: > 5,000 mg/kg body weight
Practically non-toxic.
FIFRA category IV.
Acute dermal toxicity
Rat, LD50: > 5,000 mg/kg body weight
Practically non-toxic.
FIFRA category IV.
No mortality.
Skin irritation
Rabbit, 3 animals, OECD 404 test:
Days to heal: 1
Primary Irritation Index (PII): 0.3/8.0
Essentially non irritating.
FIFRA category IV.
Acute inhalation toxicity
Rat, LC50 (limit test), 4 hours, aerosol:
Practically non-toxic.
FIFRA category IV.
No mortality. No 4-hr LC50 at the maximum tested concentration. Not hazardous for transportation.
Skin sensitization
Guinea pig, 3-induction Buehler test:
Positive incidence: 0 %
N-(phosphonomethyl)glycine; {glyphosate}
Mutagenicity
In vitro and in vivo mutagenicity test(s):
Not mutagenic.
Repeated dose toxicity
Rabbit, dermal, 21 days:
NOAEL toxicity: > 5,000 mg/kg body weight/day
Target organs/systems: none
Other effects: none
Rat, oral, 3 months:
NOAEL toxicity: > 20,000 mg/kg diet
Target organs/systems: none
Other effects: none
Chronic effects/carcinogenicity
Mouse, oral, 24 months:
NOEL tumour: > 30,000 mg/kg diet
NOAEL toxicity: ~ 5,000 mg/kg diet
Tumours: none