Technical data

39
“PRECISION/lq” Kit
The “PRECISION/lq” Offline Kit represents the
standard USP/EP compliant ERWEKA Offline
system with high precision dosing (± 0.1 ml),
standard media replacement, HLPC Vial mem-
brane piercing and optional dilution function.
The system comprises of:
1.) Fully USP/EP compliant sampling station
with automatic sample withdraw height ad-
justment and 7 stainless steel (316) sam-
ple withdraw tubes
2.) 7-channel syringe pump SP 725/10 with 10
ml syringes and mechanically operated
valves
3.) FRL 720 7-channel “silent” Autosampler
with x/y driven arm in “corrosion reduced
design” for collection of up to 25 sampling
intervals into 10 ml glass tubes, sealed
1.2/4.0 ml HPLC vials or 17 sampling in-
tervals into 25 ml glass tubes as well as
support arm to hold a rack.
4.) Tubing/Connector Kit, Teflon
5.) System pre-configuration
6.) Upgraded micro-controller for DT 820 se-
ries to control the complete Offline System
Not included: DT 820 dissolution tester and
collection rack.
Operation principle:
The stainless steel (optional Titanium) sample
withdraw tubes are driven into the media (ex-
actly midway between the top of the media and
the top of the rotating Basket or Paddle) only
while the sample is withdrawn – not to change
the hydrodynamic inside the vessel – as de-
scribed in the USP and EP.
Optional the sample withdraw system can be
equipped with electronic temperature sensors
for each vessel to archive media temperature
documentation for each test-station.
The connected 7-channel syringe Pump SP
725/10 sucks the media through the filter and
Teflon tubing to the syringe, passing a motor
driven, mechanical 4-way switching valve with
inert interior. Then the valves switch and the
new Teflon coated, 2-part pistons push the
sample into the waiting glass tubes or
sealed/unsealed HPLC vials (membrane pierc-
ing standard).
The FRL 720 Autosampler allows storage of up
to 25 (glass tubes of 10 ml-, HPLC vials of 1.5
or 4.0 ml capacity) or 17 (glass tubes of 25 ml
capacity) sampling intervals.
Optionally cooled racks for HPLC vials are
available. After sample collection the 316
stainless steel tubes (optionally Titanium) of the
Autosampler drive down into the replacement
media inside the acrylic glass reservoir which
refills after each media replacement interval
automatically by two integrated 1-channel peri-
staltic pumps. The syringes will transfer the
desired volume to the test-stations to keep the
media volume within the USP/EP specified ±
1% limits.
The FRL 720 in combination with the syringe
pump and 10/25 ml glass tubes allows auto-
mated dilution of the sample in the 1:1, 1:2, 1:5
and 1:10 relations.
“PRECISION/lq” Offline Kit, 7-channel
15-127-0000
(storage/precision doses into tubes & HPLC vials, media replacement and HPLC vial
membrane piercing)