Basic Documentation
Table Of Contents
- Introduction
- Applicable Definitions (Alphabetical Listing)
- Laboratory Safety
- Hazard Assessment
- Chemical Hygiene Plan
- Chemical Hygiene Responsibilities
- Fume Hoods
- When Required & Safe Usage
- Gloveboxes:
- Face Velocity
- Face Velocity Setback
- Size & ADA Compliance
- CAV (Constant Air Volume) Bypass
- CAV (Constant Air Volume) Conventional
- VAV (Variable Air Volume)
- VAV Diversity
- Automatic Sash Closure
- Safe Operation of Sashes
- Accessories, Services and Explosion Protection
- Ductless
- Auxiliary Air
- (Special Purpose) Perchloric Acid
- Room Air Cross Currents
- Minimum Exhaust
- Monitoring
- Selection Criteria and Performance Specifications
- Laboratory Design & Fume Hood Implementation
- Maintenance
- Periodic Testing
- Test Procedures
- Signage and Recordkeeping
- Shutdown Procedures
- Evaluating CAV (Constant Air Volume) Systems
- Evaluating VAV (Variable Air Volume) Systems
- Biological Laboratories
- Biosafety Level 1
- Biosafety Level 2
- Biosafety Level 3
- Biosafety Level 4
- Ventilation for Biosafety Level 1
- Ventilation for Biosafety Level 2
- Ventilation for Biosafety Level 3
- Ventilation for Biosafety Level 4, Cabinet Laboratory
- Ventilation for Biosafety Level 4, Suit Laboratory
- Containment Levels - Canada
- Containment Levels and Ventilation Requirements: Canada
- Biological Safety Cabinets and Classifications
- Biosafety Cabinet Applications
- Biosafety Cabinets – Installation and Safe Usage Recommendations
- Biosafety Cabinets – Certification and Safe Usage - Canada
- Biological Safety Cabinet Design, Construction and Performance Requirements
- Biosafety Cabinet Testing
- Ventilation Systems
- Local Ventilation -When Required
- Ventilation Rates for Animal Rooms
- Ventilation Rates for Animal Rooms
- Ventilation Rates for Biological Labs
- Ventilation Rates for Chemical Laboratories
- Ventilation rates for Storage areas
- Room Supply Air
- Supply Air Quality and Filtration
- Room and Duct Pressurization
- Human Occupancy, Room Temperature and Humidity
- Animal Rooms Room Temperature and Humidity
- Load Calculations
- Room Sound Level and Vibration
- Emergency Control Provisions
- Energy Conservation
- Monitoring
- Maintenance
- Periodic Inspection and Testing
- Periodic Inspection and Testing - Canada
- Test Records
- Management
- Exhaust Systems
- Configuration
- Leakage
- Components
- Manifolded Systems
- Air Velocity
- Stack Height and Discharge Location
- Operational Reliability
- Recirculated Air and Cross Contamination
- Materials and Fire Protection
- Commissioning
- Commissioning - Canada
- Referenced Publications
Applicable Definitions (Alphabetical Listing)
Siemens Industry, Inc. 7
Term Definition Commentary
Autoclave
Barriers – Primary &
Secondary
Biohazard
Biohazardous
Biological Safety
Cabinet
Biosafety Cabinet
A laboratory facility appliance used to destroy biohazardous waste and sterilize certain
apparatus by means of high temperatures. Autoclaves come in various sizes and
arrangements and commonly use pressurized steam as the sterilizing agent.
A barrier is a means of protection against contact with potentially harmful chemical or
biological agents. Primary barriers commonly include fume hoods, biosafety cabinets
and gloveboxes which provide protection by limiting the size of opening(s) to the interior
and also maintain a constant inward airflow through the opening(s) to prevent
hazardous agents from escaping. (Gloveboxes provide maximum protection by not
having any opening to the interior.) Secondary barriers commonly consist of the
laboratory room itself. The room ventilation system design which normally must provide
a constant inward airflow through any openings (doorways) to prevent potentially
contaminated air from flowing out of the room, along with air filtering, room airlocks and
even redundant ventilation equipment can be considered part of the secondary barrier.
Biohazard or biohazardous refers to a situation where there is the potential for exposure
to or direct contact with a disease causing agent. Such agents include anything that is
capable of causing diseases in humans and/or animals and includes viruses, microbes
and sub viral agents. Aside from the biohazard agent itself, biohazards include the
products of such agents as well as materials that may harbor biohazardous agents.
Often these consist of human blood, body fluids, body wastes or tissues that may be or
may have been contaminated with biohazardous agents.
A ventilated cabinet for personnel, product and environmental protection having an
open front with inward airflow for personnel protection, downward HEPA filtered laminar
airflow for product protection, and HEPA filtered exhaust air for environmental
protection. (Also see Biological Laboratories, Biological Safety Cabinets and
Classifications in this document.)
The presence of a biohazard cannot always
be known beforehand. For instance, it cannot
always be known if a tissue sample or other
item is or is not infectious. Therefore it must
be assumed when working with such items
that a biohazard does exist and following
appropriate safety measures and proper work
procedures must be followed.