Basic Documentation

Ventilation Systems
Siemens Industry, Inc. 129
Topic Requirement(s) Commentary
Periodic
Inspection
and Testing -
Canada
(Continued)
9. Supply and exhaust air ductwork between containment perimeter and HEPA filter
or bubble tight backdraft damper to be tested in situ by pressure decay method in
accordance with ASME N510(2). Acceptance criteria: rate of air leakage not to
exceed 0.1% duct vol/min at 1000 Pa (4 in. w.g.) minimum test pressure.
10. Pressurization relationships across adjacent areas to be verified (that is, clean
change to dirty change, dirty change to laboratory). Acceptance criteria: inward
directional airflow (under normal operations) to be visually demonstrated (e.g., by
holding a smoke pencil at each door leading to adjacent areas).
11. Control systems to be tested for fail-safe operation by failure of system
components, (that is, exhaust fan failure, supply fan failure, power failure [where
possible], Class II B2 BSC exhaust failure). This is to include audible/visual alarm
testing. Acceptance criteria: inward directional airflow. The sustained reversal of
airflow across containment barrier is to be prevented. This test is not a mandatory
requirement for recertification if no control system hardware or logic changes or
upgrades have been done; if modifications have been performed, or if frequent
control system problems or failures have been encountered, then the requirement
for retesting should be determined in consultation with the Biological Safety
Officer/ Institutional Biosafety Committee. Note, this may necessitate the need for
decontamination. While not required annually, control systems should be retested
periodically. Consult Manufacturer's specifications.
12. Supply and exhaust air ductwork between containment perimeter and HEPA filter
or bubble tight backdraft damper to be tested in situ by pressure decay method in
accordance with ASME N510(2). Acceptance criteria: rate of air leakage not to
exceed 0.1% duct vol/min at 1000 Pa (4 in. w.g.) minimum test pressure.
13. Pressurization relationships across adjacent areas to be verified (that is, clean
change to dirty change, dirty change to laboratory). Acceptance criteria: inward
directional airflow (under normal operations) to be visually demonstrated (e.g., by
holding a smoke pencil at each door leading to adjacent areas).
14. Control systems to be tested for fail-safe operation by failure of system
components, (that is, exhaust fan failure, supply fan failure, power failure [where
possible], Class II B2 BSC exhaust failure). This is to include audible/visual alarm
testing. Acceptance criteria: inward directional airflow. The sustained reversal of
airflow across containment barrier is to be prevented. This test is not a mandatory
requirement for recertification if no control system hardware or logic changes or
upgrades have been done; if modifications have been performed, or if frequent
control system problems or failures have been encountered, then the requirement
for retesting should be determined in consultation with the Biological Safety
Officer/ Institutional Biosafety Committee. Note, this may necessitate the need for
decontamination. While not required annually, control systems should be retested
periodically. Consult Manufacturer's specifications.
Footnotes for Containment Level 4 (CL4) Testing Requirements are listed on the
following page.