Basic Documentation
Table Of Contents
- Introduction
- Applicable Definitions (Alphabetical Listing)
- Laboratory Safety
- Hazard Assessment
- Chemical Hygiene Plan
- Chemical Hygiene Responsibilities
- Fume Hoods
- When Required & Safe Usage
- Gloveboxes:
- Face Velocity
- Face Velocity Setback
- Size & ADA Compliance
- CAV (Constant Air Volume) Bypass
- CAV (Constant Air Volume) Conventional
- VAV (Variable Air Volume)
- VAV Diversity
- Automatic Sash Closure
- Safe Operation of Sashes
- Accessories, Services and Explosion Protection
- Ductless
- Auxiliary Air
- (Special Purpose) Perchloric Acid
- Room Air Cross Currents
- Minimum Exhaust
- Monitoring
- Selection Criteria and Performance Specifications
- Laboratory Design & Fume Hood Implementation
- Maintenance
- Periodic Testing
- Test Procedures
- Signage and Recordkeeping
- Shutdown Procedures
- Evaluating CAV (Constant Air Volume) Systems
- Evaluating VAV (Variable Air Volume) Systems
- Biological Laboratories
- Biosafety Level 1
- Biosafety Level 2
- Biosafety Level 3
- Biosafety Level 4
- Ventilation for Biosafety Level 1
- Ventilation for Biosafety Level 2
- Ventilation for Biosafety Level 3
- Ventilation for Biosafety Level 4, Cabinet Laboratory
- Ventilation for Biosafety Level 4, Suit Laboratory
- Containment Levels - Canada
- Containment Levels and Ventilation Requirements: Canada
- Biological Safety Cabinets and Classifications
- Biosafety Cabinet Applications
- Biosafety Cabinets – Installation and Safe Usage Recommendations
- Biosafety Cabinets – Certification and Safe Usage - Canada
- Biological Safety Cabinet Design, Construction and Performance Requirements
- Biosafety Cabinet Testing
- Ventilation Systems
- Local Ventilation -When Required
- Ventilation Rates for Animal Rooms
- Ventilation Rates for Animal Rooms
- Ventilation Rates for Biological Labs
- Ventilation Rates for Chemical Laboratories
- Ventilation rates for Storage areas
- Room Supply Air
- Supply Air Quality and Filtration
- Room and Duct Pressurization
- Human Occupancy, Room Temperature and Humidity
- Animal Rooms Room Temperature and Humidity
- Load Calculations
- Room Sound Level and Vibration
- Emergency Control Provisions
- Energy Conservation
- Monitoring
- Maintenance
- Periodic Inspection and Testing
- Periodic Inspection and Testing - Canada
- Test Records
- Management
- Exhaust Systems
- Configuration
- Leakage
- Components
- Manifolded Systems
- Air Velocity
- Stack Height and Discharge Location
- Operational Reliability
- Recirculated Air and Cross Contamination
- Materials and Fire Protection
- Commissioning
- Commissioning - Canada
- Referenced Publications
Laboratory Ventilation Codes and Standards
Siemens Industry, Inc. 12
Term Definition Commentary
Glovebox
Hazardous Chemical
HEPA & ULPA Filters
Hood:
Canopy Hood
Hood:
Clean Bench or
Laminar Flow Hood
Hood:
Slot Hood
A fully enclosed protective enclosure in which a user gains access to the inside by
inserting their hands into impervious gloves which are permanently attached to one or
more sides of the glovebox. A glovebox is used when chemical or biological
substances are too hazardous to be manipulated in a regular fume hood or biological
safety cabinet or in certain instances where the substance itself requires an extremely
high degree of protection (that is, a highly sterile ambient). Also known as a Class III
BSC.
U.S. OSHA: “A chemical for which there is statistically significant evidence based on at
least one study conducted in accordance with established scientific principles that
acute or chronic health effects may occur in exposed employees. The term "health
hazard" includes chemicals which are carcinogens, toxic or highly toxic agents,
reproductive toxins, irritants, corrosives, sensitizers, hepatotoxins, nephrotoxins,
neurotoxins, agents which act on the hematopoietic systems and agents which damage
the lungs, skin, eyes, or mucous membranes.”
High Efficiency Particulate Air filter and Ultra Low Penetrating Air filter. Very highly
efficient paper air filters. HEPA filters trap at least 99.97% of particles as small as 0.3
microns (0.00001 inches) in diameter at a rated airflow velocity. ULPA filters trap at
least 99.999% of particles as small as 0.1 to 0.2 microns (0.000004 to 0.000008
inches) in diameter at a rated airflow velocity. They both have a rigid casing that
encloses the full depth of the pleats. When new, HEPA & ULPA filters should have a
maximum pressure drop of 1.0 inch w. g. (250 Pa). HEPA filters should conform to all
requirements of a Type C filter, while ULPA filters should conform to all requirements of
a Type F filter per the Institute of Environmental Sciences and Technology's Filter
Standard: IEST-RP-CC001.
A containment unit with an open bottom that is suspended above a process or some
equipment that requires (or will benefit from) an overhead exhaust provision. Canopy
hoods are the standard type of exhaust hood used for cooking applications to remove
heat, steam and grease vapors. In laboratories they are normally utilized to remove
excess heat, water vapor and other non-toxic fumes that rise above certain equipment.
A ventilated enclosure intended to also provide clean filtered air to protect the contents
of the hood and exhaust fumes generated internally. Such hoods are used for acid
digestion research and for applications where the contents (micro-electronic circuits,
etc.) need to be kept free from contamination by unfiltered room air.
A narrow vertical hood that is typically set up for horizontal applications such as on the
side of a workbench (rather than above) to exhaust non-toxic elements such as
particulate, dust and other airborne fumes close to room temperature.
Various models of gloveboxes are available
including some for high containment and
medium containment applications. Those used
mainly for user protection have a dedicated
filtered exhaust system to ensure the interior is
always under a negative pressure (slight
vacuum) to prevent interior air from leaking
into the room. Dangerous substances are put
into or removed from the interior by special
airlock type drawer arrangements and the use
of tightly sealed containers that are only open
when inside the glovebox. Gloveboxes are
also available with air purging systems to
facilitate internal purification and a provision to
maintain specific internal ambient conditions.
HEPA filters provide the cleanest practical
airflow for most ventilation system applications
and are typically applied to cleanroom supply
and exhaust systems. Biosafety cabinets use
HEPA filters to provide clean air to protect the
contents and to filter the exhaust before it is
released into the atmosphere.
Although HEPA and ULPA filters will trap
virtually all airborne particulate, including
bacteria, they will not trap chemical fumes or
gasses.