Basic Documentation

Laboratory Ventilation Codes and Standards
Siemens Industry, Inc. ii
Biosafety Level 2 .......................................................................................................... 58
Biosafety Level 3 .......................................................................................................... 59
Biosafety Level 4 .......................................................................................................... 61
Ventilation for Biosafety Level 1 ................................................................................... 63
Ventilation for Biosafety Level 2 ................................................................................... 64
Ventilation for Biosafety Level 3 ................................................................................... 65
Ventilation for Biosafety Level 4, Cabinet Laboratory .................................................. 67
Ventilation for Biosafety Level 4, Suit Laboratory ........................................................ 68
Containment Levels - Canada ..................................................................................... 70
Containment Levels and Ventilation Requirements: Canada ...................................... 71
Biological Safety Cabinets and Classifications ............................................................ 75
Biosafety Cabinet Applications .................................................................................... 86
Biosafety Cabinets – Installation and Safe Usage Recommendations ........................ 88
Biosafety Cabinets – Certification and Safe Usage - Canada ..................................... 90
9.3 Installation and Certification ................................................................................ 90
Biological Safety Cabinet Design, Construction and Performance Requirements ...... 92
Biosafety Cabinet Testing ............................................................................................ 93
Ventilation Systems ........................................................................................................ 96
Local Ventilation -When Required ............................................................................... 96
Ventilation Rates for Animal Rooms ............................................................................ 97
Ventilation Rates for Animal Rooms ............................................................................ 99
Ventilation Rates for Biological Labs ........................................................................... 99
Ventilation Rates for Chemical Laboratories.............................................................. 100
Ventilation rates for Storage areas ............................................................................ 100
Room Supply Air ........................................................................................................ 101
Supply Air Quality and Filtration ................................................................................. 103
Room and Duct Pressurization .................................................................................. 105
Human Occupancy, Room Temperature and Humidity ............................................. 107
Animal Rooms Room Temperature and Humidity ..................................................... 108
Load Calculations ....................................................................................................... 110
Room Sound Level and Vibration .............................................................................. 111
Emergency Control Provisions ................................................................................... 114
Energy Conservation .................................................................................................. 116
Monitoring .................................................................................................................. 119
Maintenance ............................................................................................................... 121
Periodic Inspection and Testing ................................................................................. 122
Periodic Inspection and Testing - Canada ................................................................. 124
5.3 Air Handling Systems ........................................................................................ 126
Test Records .............................................................................................................. 131
Management .............................................................................................................. 131
Exhaust Systems ........................................................................................................... 132
Configuration .............................................................................................................. 132
Leakage ..................................................................................................................... 135
Components ............................................................................................................... 136