User Manual

The combination of these two sensors also prevents rate increases due to artifacts through
continuous cross-checking of information from each sensor. Any rate increase not confirmed
by the second sensor results in a return to the basic escape rate.
In dual sensor mode (Twin Trace), the MV sensor is dominant and solely determines the rate
response when both sensors detect exercise.
The rate-responsive mode, the sensor choice and the physical activity are the only
parameters to be programmed.
As long as the patient is at rest, the sensor-driven rate is equal to the basic rate. When
the patient reaches his maximum exercise capacity, the sensor-driven rate is equal to the
maximum rate. During exercise, the rate variation is proportional to the measured sensor
level. The programmed physical activity determines the relationship between the measured
sensor level and the sensor-driven rate.
Rate response can be programmed:
For the SR model: only if the pacing mode is programmed to AAIR or VVIR.
For the DR model: only if the pacing mode is programmed to SafeR-R, SafeR/DDIR, Dplus-
R, Dplus/DDIR, AAIR, DDDR, DDD/DDIR, DDIR, VVIR.
Examples:
1. Automatic rate response ("RR Auto" option). The pacing rate is constantly adapted to the
patient's physical activity.
2. Manual rate response ("RR Fixed" option). In that case, manual programming of the
patient's physical activity determines the pacing rate applied, based on the sensor
signal.The physical activity parameter should be programmed according to the patient’s
activity level, to which ALIZEA associates the maximum rate. It is recommended to
program very low or low values for sedentary patients and high or very high values for
active patients.
3. For the DR model, rate response during fallback mode switching (SafeR/DDIR,
DDD/DDIR and Dplus/DDIR modes). Rate response is inactive if the patient is in sinus
rhythm. It becomes active during atrial arrhythmia.
WARNINGS: Use the Rate Response function with caution in cases of:
1. Severe coronary insufficiency.
2. Severe aortic stenosis.
3. Myocardial function compromised by undue accelerations of the pacing rate.
Programming at implant:
"Learn" and "RR Auto" should not be programmed prior to implant so as not to distort
autocalibration.
Surgical procedure:
For safety reasons, it is preferable to deprogram the Rate Response function before any
surgical procedure on the pacemaker patient.
Programming requirement:
For the DR model: The SafeR/DDIR, DDD/DDIR and Dplus/DDIR modes (Rate response
during fallback mode switching) are accessible only if Fallback mode switching is
programmed.
15. FUNCTIONS AND PARAMETERS
42 ALIZEA – UA10414A